| Literature DB >> 23735698 |
Abstract
We consider biomacromolecular crowding within the cytoplasm of prokaryotic cells as a two-phase system of 'supercrowded' cytogel and 'dilute' cytosol; we simplify and quantify this model for a coccoid cell over a wide range of biomacromolecular crowding. The key result shows that the supercrowded cytogel extends the vectorial character of the plasma membrane deeper into the cytoplasm by about 20-70 nm. We discuss useful physiological insights that this model gives into the functioning of a prokaryotic cell on the micrometer scale.Mesh:
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Year: 2013 PMID: 23735698 DOI: 10.1016/j.febslet.2013.05.051
Source DB: PubMed Journal: FEBS Lett ISSN: 0014-5793 Impact factor: 4.124