Literature DB >> 23735521

Medical comorbidities in disorders of consciousness patients and their association with functional outcomes.

Shanti Ganesh1, Ann Guernon, Laura Chalcraft, Brett Harton, Bridget Smith, Theresa Louise-Bender Pape.   

Abstract

OBJECTIVE: To identify, for patients in states of seriously impaired consciousness, comorbid conditions present during inpatient rehabilitation and their association with function at 1 year.
DESIGN: Abstracted data from a prospective cross-sectional observational study with data collection occurring January 1996 through December 2007.
SETTING: Four inpatient rehabilitation facilities in metropolitan areas. PARTICIPANTS: The study sample of 68 participants is abstracted from a database of 157 patients remaining in states of seriously impaired consciousness for at least 28 days.
INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURE: One-year cognitive, motor, and total FIM score.
RESULTS: The most common medical complications during inpatient rehabilitation for the study sample are active seizures (46%), spasticity (57%), urinary tract infections (47%), and hydrocephalus with and without shunt (38%). Presence of ≥3 medical complications during inpatient rehabilitation, controlling for injury severity, is significantly (P<.05) associated with poorer total FIM and FIM motor scores 1 year after injury. The presence of hydrocephalus with and without shunt (r=-.20, -.21, -.18; P ≤.15), active seizures (r=-.31, -.22, -.42), spasticity (r=-.38, -.28, -.40), and urinary tract infections (r=-.25, -.24, -.26) were significantly (P<.10) associated with total FIM, FIM cognitive, and FIM motor scores, respectively.
CONCLUSIONS: Reported findings indicate that persons in states of seriously impaired consciousness with higher numbers of medical complications during inpatient rehabilitation are more likely to have lower functional levels 1-year postinjury. The findings indicate that persons with ≥3 medical complications during inpatient rehabilitation are at a higher risk for poorer functional outcomes at 1 year. It is, therefore, prudent to evaluate these patients for indications of these complications during inpatient rehabilitation.
Copyright © 2013 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  BI; Brain injuries; Comorbidity; Consciousness disorders; PTE; Rehabilitation; SMR; TBI; UTI; brain injury; posttraumatic epilepsy; standard mortality ratio; traumatic brain injury; urinary tract infection

Mesh:

Year:  2013        PMID: 23735521     DOI: 10.1016/j.apmr.2012.12.026

Source DB:  PubMed          Journal:  Arch Phys Med Rehabil        ISSN: 0003-9993            Impact factor:   3.966


  16 in total

1.  Long-term outcome of patients with disorders of consciousness with and without epileptiform activity and seizures: a prospective single centre cohort study.

Authors:  Angelo Pascarella; Luigi Trojano; Vincenzo Loreto; Leonilda Bilo; Pasquale Moretta; Anna Estraneo
Journal:  J Neurol       Date:  2016-07-14       Impact factor: 4.849

2.  Multicentre registry of brain-injured patients with disorder of consciousness: rationale and preliminary data.

Authors:  A Pascarella; S Fiorenza; O Masotta; V Tibollo; D Vella; Anna Maria Nardone; Marta Rossi; P Volanti; F Madonia; Gaetano Cstronovo; D De Cicco; Caterina Guarnaschelli; M P Achilli; C Chiapparino; M T Angelillo; M A Tommasi; F Pisano; G Grioni; G Vezzadini; G Ferriero; S Salvaderi; R Bellazzi; Anna Estraneo
Journal:  Funct Neurol       Date:  2018 Jan/Mar

3.  [Factors affecting recovery of consciousness in patients with disorders of consciousness following brain trauma: a logistic regression analysis].

Authors:  Qing Lin; Qiu-You Xie; Yan-Bin He; Yan Chen; Xiao-Xiao Ni; Ye-Qun Guo; Yan Shen; Rong-Hao Yu
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2017-03-20

Review 4.  A Systematic Review of Comorbidity Measurement Methods for Patients With Nontraumatic Brain Injury in Inpatient Rehabilitation Settings.

Authors:  Wayne Khuu; Vincy Chan; Angela Colantonio
Journal:  Am J Phys Med Rehabil       Date:  2017-11       Impact factor: 2.159

Review 5.  Practice guideline update recommendations summary: Disorders of consciousness: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology; the American Congress of Rehabilitation Medicine; and the National Institute on Disability, Independent Living, and Rehabilitation Research.

Authors:  Joseph T Giacino; Douglas I Katz; Nicholas D Schiff; John Whyte; Eric J Ashman; Stephen Ashwal; Richard Barbano; Flora M Hammond; Steven Laureys; Geoffrey S F Ling; Risa Nakase-Richardson; Ronald T Seel; Stuart Yablon; Thomas S D Getchius; Gary S Gronseth; Melissa J Armstrong
Journal:  Neurology       Date:  2018-08-08       Impact factor: 9.910

6.  Evaluation of functional outcomes in traumatic spinal cord injury with rehabilitation-acquired urinary tract infections: A retrospective study.

Authors:  Argyrios Stampas; Elizabeth Dominick; Liang Zhu
Journal:  J Spinal Cord Med       Date:  2018-04-03       Impact factor: 1.985

7.  Concordance between current American Academy of Sleep Medicine and Centers for Medicare and Medicare scoring criteria for obstructive sleep apnea in hospitalized persons with traumatic brain injury: a VA TBI Model System study.

Authors:  Risa Nakase-Richardson; Marie N Dahdah; Emily Almeida; Peter Ricketti; Marc A Silva; Karel Calero; Ulysses Magalang; Daniel J Schwartz
Journal:  J Clin Sleep Med       Date:  2020-06-15       Impact factor: 4.062

8.  Prescribing multiple neurostimulants during rehabilitation for severe brain injury.

Authors:  Amy A Herrold; Theresa Louise-Bender Pape; Ann Guernon; Trudy Mallinson; Eileen Collins; Neil Jordan
Journal:  ScientificWorldJournal       Date:  2014-12-22

Review 9.  Interrelation between Neuroendocrine Disturbances and Medical Complications Encountered during Rehabilitation after TBI.

Authors:  Caroline I E Renner
Journal:  J Clin Med       Date:  2015-09-22       Impact factor: 4.241

Review 10.  Spasticity Management in Disorders of Consciousness.

Authors:  Géraldine Martens; Steven Laureys; Aurore Thibaut
Journal:  Brain Sci       Date:  2017-12-09
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