Literature DB >> 23735326

Intracellular observation of nanocarriers modified with a mitochondrial targeting signal peptide.

Eriko Kawamura1, Yuma Yamada, Yukari Yasuzaki, Mamoru Hyodo, Hideyoshi Harashima.   

Abstract

This study focused on the intracellular observation of nanocarriers modified with a mitochondrial targeting signal peptide (MTS). The nanocarriers showed an efficient cellular uptake, and the MTS had a positive effect on their mitochondrial targeting. This is the first report of an intracellular observation of nanocarriers modified with MTS.
Copyright © 2013 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  MITO-Porter; Mitochondria; Mitochondrial drug delivery; Mitochondrial targeting signal peptide (MTS); Nanocarriers; Nanotechnology

Mesh：

Substances：

Year:  2013        PMID： 23735326     DOI： 10.1016/j.jbiosc.2013.05.001

Source DB:  PubMed          Journal:  J Biosci Bioeng        ISSN： 1347-4421            Impact factor:   2.894


  6 in total

Review 1.  Pharmacological modulation of mitochondrial ion channels.

Authors:  Luigi Leanza; Vanessa Checchetto; Lucia Biasutto; Andrea Rossa; Roberto Costa; Magdalena Bachmann; Mario Zoratti; Ildiko Szabo
Journal:  Br J Pharmacol       Date:  2019-01-02       Impact factor: 8.739

2.  Delivery of mitochondriotropic doxorubicin derivatives using self-assembling hyaluronic acid nanocarriers in doxorubicin-resistant breast cancer.

Authors:  Hui-Na Liu; Ning-Ning Guo; Wang-Wei Guo; Ming-Yi Huang-Fu; Mohammad Reza Vakili; Jie-Jian Chen; Wen-Hong Xu; Qi-Chun Wei; Min Han; Afsaneh Lavasanifar; Jian-Qing Gao
Journal:  Acta Pharmacol Sin       Date:  2018-05-31       Impact factor: 6.150

Review 3.  Active Cellular and Subcellular Targeting of Nanoparticles for Drug Delivery.

Authors:  Okhil K Nag; James B Delehanty
Journal:  Pharmaceutics       Date:  2019-10-18       Impact factor: 6.321

4.  Condensation of plasmid DNA enhances mitochondrial association in skeletal muscle following hydrodynamic limb vein injection.

Authors:  Yukari Yasuzaki; Yuma Yamada; Yutaka Fukuda; Hideyoshi Harashima
Journal:  Pharmaceuticals (Basel)       Date:  2014-08-21

Review 5.  Mitochondrion: A Promising Target for Nanoparticle-Based Vaccine Delivery Systems.

Authors:  Ru Wen; Afoma C Umeano; Lily Francis; Nivita Sharma; Smanla Tundup; Shanta Dhar
Journal:  Vaccines (Basel)       Date:  2016-06-01

6.  Mitochondria-targeted delivery of doxorubicin to enhance antitumor activity with HER-2 peptide-mediated multifunctional pH-sensitive DQAsomes.

Authors:  Menghao Shi; Jiulong Zhang; Xiaowei Li; Shuang Pan; Jie Li; Chunrong Yang; Haiyang Hu; Mingxi Qiao; Dawei Chen; Xiuli Zhao
Journal:  Int J Nanomedicine       Date:  2018-07-18
  6 in total

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