| Literature DB >> 23734676 |
Maxim O Ratnikov1, Xinfang Xu, Michael P Doyle.
Abstract
Iron(III) chloride catalyzes the aerobic oxidation of tertiary anilines, including tetrahydroisoquinolines, to form reactive iminium ion intermediates that undergo Mannich reactions with silyloxyfurans, nitroalkanes, and other nucleophiles to give the corresponding butenolides, nitro compounds, and α-substituted tetrahydroisoquinolines, respectively, in good to excellent yields.Entities:
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Year: 2013 PMID： 23734676 DOI： 10.1021/ja402479r
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419