New developments in arterial spin labeling pulse sequences.

Since it was introduced over 20 years ago, arterial spin labeling and related methods have steadily evolved over the years, and the field has seen not only improvements in technical specifications, such as signal-to-noise ratio and accuracy, but also the introduction of methods that allow for the collection of new information, such as maps of vascular territories and measurement of venous oxygenation. Some of these recent advances are reviewed here.