Literature DB >> 23733363

Influence of age on clinical outcome of acute diverticulitis.

Ç Ünlü1, B J van de Wall, M F Gerhards, M Wiezer, W A Draaisma, E C Consten, M A Boermeester, B C Vrouenraets.   

Abstract

BACKGROUND: The controversy about the treatment of acute colonic diverticulitis in young patients continues. The discussion is focused on whether younger age is a risk factor for recurrence or a complicated course, thereby subject to different treatment choices. AIM: In this study, we investigated whether an episode of acute diverticulitis at a younger age (≤50 years) has a higher recurrence rate or a more severe outcome.
MATERIAL AND METHODS: A retrospective cohort study was conducted in four teaching hospitals using hospital registry codes for diverticulitis. All patients diagnosed with acute diverticulitis between January 2004 and January 2012, confirmed by imaging, were included.
RESULTS: A total of 1,441 consecutive patients were identified as having primary acute diverticulitis of the sigmoid colon. Four hundred and sixty-three patients (32.1%) were ≤50 years (group 1) and 978 patients (67.9%) were older than 50 years (group 2). Twenty patients (4.3%) needed emergency surgery, due to perforated diverticulitis, within 72 h at first presentation in group 1 compared to 77 patients (7.8%) in group 2 (p = 0.029). Surgery within 30 days was needed for 29 of 463 patient (6.2%) in group 1 and 104 of 978 patients (10.6%) in group 2 (p = 0.02). Recurrence rate after a median follow-up of 22 months was comparable among groups (25.6% (111 patients) in group 1 versus 23.8% (208 patients) in group 2; p = 0.278). Also, cumulative recurrence was comparable among groups.
CONCLUSION: Younger age is neither associated with a more severe presentation of diverticulitis nor with a higher incidence in recurrence.

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Year:  2013        PMID: 23733363     DOI: 10.1007/s11605-013-2240-3

Source DB:  PubMed          Journal:  J Gastrointest Surg        ISSN: 1091-255X            Impact factor:   3.452


  15 in total

1.  Diagnosis and management of diverticular disease of the colon in adults. Ad Hoc Practice Parameters Committee of the American College of Gastroenterology.

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Journal:  Am J Gastroenterol       Date:  1999-11       Impact factor: 10.864

2.  Surgical treatment of diverticulitis. Patient Care Committee of the Society for Surgery of the Alimentary Tract (SSAT).

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Journal:  J Gastrointest Surg       Date:  1999 Mar-Apr       Impact factor: 3.452

3.  Presentation and treatment outcome of diverticulitis in younger adults: a different disease than in older patients?

Authors:  N Kotzampassakis; O Pittet; S Schmidt; A Denys; N Demartines; J M Calmes
Journal:  Dis Colon Rectum       Date:  2010-03       Impact factor: 4.585

4.  Long-term outcome of mesocolic and pelvic diverticular abscesses of the left colon: a prospective study of 73 cases.

Authors:  Patrick Ambrosetti; Roland Chautems; Claudio Soravia; Nyali Peiris-Waser; François Terrier
Journal:  Dis Colon Rectum       Date:  2005-04       Impact factor: 4.585

5.  Practice parameters for sigmoid diverticulitis.

Authors:  Janice Rafferty; Paul Shellito; Neil H Hyman; W Donald Buie
Journal:  Dis Colon Rectum       Date:  2006-07       Impact factor: 4.585

6.  Outcome of a conservative policy for managing acute sigmoid diverticulitis.

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Journal:  Br J Surg       Date:  2007-07       Impact factor: 6.939

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Authors:  Daniel A Anaya; David R Flum
Journal:  Arch Surg       Date:  2005-07

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Authors:  James Guzzo; Neil Hyman
Journal:  Dis Colon Rectum       Date:  2004-05-19       Impact factor: 4.585

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Authors:  F Hjern; T Josephson; D Altman; B Holmström; C Johansson
Journal:  Br J Surg       Date:  2008-06       Impact factor: 6.939

Review 10.  The place of elective surgery following acute diverticulitis in young patients: when is surgery indicated? An analysis of the literature.

Authors:  Simon Janes; Alan Meagher; Ian G Faragher; Susan Shedda; Frank A Frizelle
Journal:  Dis Colon Rectum       Date:  2009-05       Impact factor: 4.585

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  5 in total

Review 1.  Diverticular disease: changing epidemiology and management.

Authors:  Roshan Razik; Geoffrey C Nguyen
Journal:  Drugs Aging       Date:  2015-05       Impact factor: 3.923

Review 2.  Risk factors for recurrence after acute colonic diverticulitis: a systematic review.

Authors:  Line Hupfeld; Jakob Burcharth; Hans-Christian Pommergaard; Jacob Rosenberg
Journal:  Int J Colorectal Dis       Date:  2017-01-22       Impact factor: 2.571

Review 3.  Contemporary Review of Risk-Stratified Management in Acute Uncomplicated and Complicated Diverticulitis.

Authors:  Marja A Boermeester; David J Humes; George C Velmahos; Kjetil Søreide
Journal:  World J Surg       Date:  2016-10       Impact factor: 3.352

4.  National complicated acute diverticulitis (CADS) study: a protocol for a prospective observational scoping study for acute diverticulitis.

Authors:  Shafaque Shaikh
Journal:  BMJ Open Gastroenterol       Date:  2016-10-24

5.  Radiologic predictors for failure of non-operative management of complicated diverticulitis: a single-centre cohort study.

Authors:  Stefan Reischl; Kai Dominik Roehl; Sebastian Ziegelmayer; Helmut Friess; Marcus Richard Makowski; Dirk Wilhelm; Alexander Rudolf Novotny; Jochen Gaa; Philipp-Alexander Neumann
Journal:  Langenbecks Arch Surg       Date:  2021-06-29       Impact factor: 3.445

  5 in total

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