| Literature DB >> 23731845 |
Sonia Burrel1, David Boutolleau, Georges Azar, Serge Doan, Claire Deback, Isabelle Cochereau, Henri Agut, Eric E Gabison.
Abstract
Herpes simplex virus type 1 (HSV-1) is a leading cause of corneal blindness. Acyclovir (ACV) constitutes the standard treatment of HSV infections including herpetic keratitis (HK). HSV resistance to ACV is mainly described in immunocompromised patients. We describe two cases of ACV-resistant corneal HSV-1 in immunocompetent individuals with recurrent HK.Entities:
Keywords: Herpetic keratitis; Immunocompetent patient; Phenotypic and genotypic antiviral resistance assay; Resistance to acyclovir
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Year: 2013 PMID: 23731845 DOI: 10.1016/j.jcv.2013.05.001
Source DB: PubMed Journal: J Clin Virol ISSN: 1386-6532 Impact factor: 3.168