| Literature DB >> 23730958 |
Hyun-Suk Yeom1, Hui Li, Yu Tang, Richard P Hsung.
Abstract
Total syntheses of a series of chromane natural products that contain a cyclobutane ring are described. A unified theme in the strategy employed for all these syntheses is an oxa-[3 + 3] annulation for constructing the chromane nucleus and a stepwise cationic [2 + 2] cycloaddition for the cyclobutane formation. More importantly, the two reactions could be rendered in tandem, thereby providing an expeditious approach to this family of natural products.Entities:
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Year: 2013 PMID： 23730958 DOI： 10.1021/ol401335u
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005