Literature DB >> 23730641

Compliance to anti-diabetic drugs: observations from the diabetic clinic of a medical college in kolkata, India.

Shuvankar Mukherjee1, Biswanath Sharmasarkar, Kaushik Kumar Das, Agnihotri Bhattacharyya, Animesh Deb.   

Abstract

BACKGROUND: The poor glycaemic control among the patients with type 2 diabetes constitutes a major public health problem and a major risk factor for the development of diabetes complications. AIM OF THE STUDY: To study the compliance rate of the patients with type 2 diabetes to the prescribed medications, to find out its correlation with different socio-demographic factors and other patient characteristics and to find out the reasons behind the non-compliance, if any. SETTINGS AND
DESIGN: This cross sectional study was conducted on the patients with type 2 diabetes, who Attended the Diabetic Clinic of a Medical College in Kolkata, India. METHODS AND MATERIAL: The patients of type 2 diabetes who attended the diabetes clinic between April to August 2012 were recruited in the study by systematic random sampling and they were interviewed by using the help of a structured interview schedule. The patients who reported taking less than 80% of their prescribed anti-diabetes medicines in the preceding week and had HbA1C of < 7% were considered to be non-compliant. STATISTICAL ANALYSIS USED: The data was analyzed by using the SPSS software. The Chi-square test was used to assess the association of the compliance with the different study variables. A binary logistic regression analysis helped in identifying the factors which contributed to the non-compliance.
RESULTS: The compliance rate to the anti-diabetic drugs was found to be 57.7%. A univariate analysis showed that it decreased significantly with increasing age and that it was also significantly lower among males, illiterates, those with a poor per capita monthly income and those who had a longer duration of diabetes. It varied significantly with the type of drugs, being lowest with an oral drug and insulin combination (43.4%). No knowledge on the complications of diabetes was significantly associated with a lower compliance. The binary logistic regression also helped in identifying these as the significant contributory factors. The common reasons behind the non-compliance were forgetfulness (44.7%) and financial constraints (32.7%).
CONCLUSION: It can be concluded that the compliance to anti-diabetic drugs was quite poor among the participants. Increasing age, the male sex, illiteracy, a low monthly income and a longer duration of diabetes were significantly associated with the non compliance. A more concerning fact was the significant association of the non-compliance with the types of drug regimens and a lack of knowledge on the complications of diabetes, which emphasized the role of a repeated patient education regarding the basic aspects of diabetes.

Entities:  

Keywords:  Anti-Diabetic drugs; Compliance; Type 2 diabetes

Year:  2013        PMID: 23730641      PMCID: PMC3644439          DOI: 10.7860/JCDR/2013/5352.2876

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  16 in total

1.  The association between diabetes metabolic control and drug adherence in an indigent population.

Authors:  Joel M Schectman; Mohan M Nadkarni; John D Voss
Journal:  Diabetes Care       Date:  2002-06       Impact factor: 19.112

2.  Increasing expenditure on health care incurred by diabetic subjects in a developing country: a study from India.

Authors:  Ambady Ramachandran; Shobhana Ramachandran; Chamukuttan Snehalatha; Christina Augustine; Narayanasamy Murugesan; Vijay Viswanathan; Anil Kapur; Rhys Williams
Journal:  Diabetes Care       Date:  2007-02       Impact factor: 19.112

Review 3.  Diabetes in Asia: epidemiology, risk factors, and pathophysiology.

Authors:  Juliana C N Chan; Vasanti Malik; Weiping Jia; Takashi Kadowaki; Chittaranjan S Yajnik; Kun-Ho Yoon; Frank B Hu
Journal:  JAMA       Date:  2009-05-27       Impact factor: 56.272

4.  Patients' adherence to diabetes treatment.

Authors:  R Shobhana; R Begum; C Snehalatha; V Vijay; A Ramachandran
Journal:  J Assoc Physicians India       Date:  1999-12

5.  Factors associated with poor glycemic control among patients with type 2 diabetes.

Authors:  Maysaa Khattab; Yousef S Khader; Abdelkarim Al-Khawaldeh; Kamel Ajlouni
Journal:  J Diabetes Complications       Date:  2009-03-17       Impact factor: 2.852

6.  Non-adherence to diabetes treatment at Mulago Hospital in Uganda: prevalence and associated factors.

Authors:  Joan N Kalyango; Erisa Owino; Agatha P Nambuya
Journal:  Afr Health Sci       Date:  2008-06       Impact factor: 0.927

7.  Epidemiology of type 2 diabetes: Indian scenario.

Authors:  V Mohan; S Sandeep; R Deepa; B Shah; C Varghese
Journal:  Indian J Med Res       Date:  2007-03       Impact factor: 2.375

8.  Diabetes in Asia.

Authors:  Ambady Ramachandran; Ronald Ching Wan Ma; Chamukuttan Snehalatha
Journal:  Lancet       Date:  2009-10-28       Impact factor: 79.321

9.  Medication adherence and associated hemoglobin A1c in type 2 diabetes.

Authors:  Kimberley Krapek; Kathleen King; Susan S Warren; Karen G George; Dorothy A Caputo; Karen Mihelich; Elizabeth M Holst; Michael B Nichol; Sheng G Shi; Kevin B Livengood; Steve Walden; Teresa J Lubowski
Journal:  Ann Pharmacother       Date:  2004-07-06       Impact factor: 3.154

10.  Factors related to patient adherence to antidiabetic drug therapy.

Authors:  Heloisa Turcatto Gimenes; Maria Lúcia Zanetti; Vanderlei José Haas
Journal:  Rev Lat Am Enfermagem       Date:  2009 Jan-Feb
View more
  11 in total

1.  Medication adherence in type 2 diabetes mellitus patients during Covid-19 pandemic: a cross-sectional study from the United Arab Emirates.

Authors:  Ameena Asheq; Akram Ashames; Moawia Al-Tabakha; Nageeb Hassan; Ammar Jairoun
Journal:  F1000Res       Date:  2021-06-02

2.  Medication adherence and direct treatment cost among diabetes patients attending a tertiary healthcare facility in Ogbomosho, Nigeria.

Authors:  J Fadare; M Olamoyegun; B A Gbadegesin
Journal:  Malawi Med J       Date:  2015-06       Impact factor: 0.875

3.  Nonadherence and contributing factors among ambulatory patients with antidiabetic medications in Adama Referral Hospital.

Authors:  Belayneh Kefale Gelaw; Abdela Mohammed; Gobezie Temesgen Tegegne; Amsalu Degu Defersha; Muluneh Fromsa; Esayas Tadesse; Thrumurgan Gunasekaran; Mustefa Ahmed
Journal:  J Diabetes Res       Date:  2014-12-03       Impact factor: 4.011

4.  Drugs prescribed by general practitioners according to age, gender and socioeconomic status after adjustment for multimorbidity level.

Authors:  Jessica Skoog; Patrik Midlöv; Anders Beckman; Jan Sundquist; Anders Halling
Journal:  BMC Fam Pract       Date:  2014-11-25       Impact factor: 2.497

5.  Treatment compliance and noncompliance in psychoses.

Authors:  K Nagaraja Rao; Jitty George; C Y Sudarshan; Shamshad Begum
Journal:  Indian J Psychiatry       Date:  2017 Jan-Mar       Impact factor: 1.759

6.  The Trend of High-Dose Insulin Usage Among Patients with Diabetes in the UK: A Retrospective Study.

Authors:  Iskandar Idris; Xiaomei Peng; Xuanyao He; Dongju Liu; Elemer Balogh; Puneet Kaushik; Kate Van Brunt
Journal:  Diabetes Ther       Date:  2018-09-29       Impact factor: 2.945

7.  Adherence, satisfaction, and experience with metformin 500 mg prolonged release formulation in Indian patients with type 2 diabetes mellitus: a postmarketing observational study.

Authors:  K M Prasanna Kumar; Manoj Chawla; Ami Sanghvi; Nadiminty G Sastry; Chaitanya Kotla; Sanjeev Phatak; Sanjay Choudhari
Journal:  Int J Gen Med       Date:  2019-04-09

8.  Role of AYUSH Therapies in Modern Medicine: A Qualitative Study to Explore the Awareness and Attitudes of Doctors Towards the Utilization of Alternate System of Medicine for Diabetes Mellitus.

Authors:  Ashutosh Ojha; Utkarsh Ojha; Harsh Ojha; Abhinaya Chandrashekar; Raihan Mohammed; Rudra Trivedi; Sharvari Ugaonkar; Manan Desai; Ramesh Sreevidya; Pratiksha Sahu
Journal:  Int J Gen Med       Date:  2020-01-13

Review 9.  Neurological Manifestation of Incretin-Based Therapies in Patients with Type 2 Diabetes: A Systematic Review and Network Meta-Analysis.

Authors:  Le Gao; Shuqing Yu; Andrea Cipriani; Shanshan Wu; Yi Huang; Zilu Zhang; Jun Yang; Yixin Sun; Zhirong Yang; Sanbao Chai; Yuan Zhang; Linong Ji; Siyan Zhan; Feng Sun
Journal:  Aging Dis       Date:  2019-12-01       Impact factor: 6.745

10.  Factors Influencing Administration, Recognition, and Compliance of Medicine among Community Residents from Jilin Province, China: A Questionnaire Study.

Authors:  Yan-Qing Song; Wen-Rui Zhang; Si-Xi Zhang; Ting-Hong Wang; Zhe Jiang; Chun-Feng Meng; Tian-Zhen Zhang; Qi-Zhong Xin; Ke-Jun Cao; Yue Zhang; Ying Sun
Journal:  Biomed Res Int       Date:  2020-07-18       Impact factor: 3.411

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.