Literature DB >> 23730573

The utility of second look microlaryngoscopy after trans oral laser resection of laryngeal cancer.

Ashok M Shenoy1, V Prashanth, T Shivakumar, Purushottam Chavan, S Akshay, Rekha V Kumar, Saraswati Devi.   

Abstract

In the past few decades more and more number of tumors of the glottis and supraglottis are been treated with single stage transoral laser microsurgery (TOLS). TOLS for the treatment of glottic and supraglottic carcinoma with anterior commissure (A-com) and/paraglottic space involvement is associated with a high rate of recurrence. We prospectively evaluated the outcomes of laser microsurgery and the impact of second look operation in these patients. Twenty-three patients with glottic and supraglottic carcinoma underwent transoral laser micro resection of the lesions. Subsequently five patients underwent second look microlaryngeal evaluation 6-8 months later for non-satisfactory healing, poor voice, and or suspicion of recurrent disease. Patients with A-com involvement and or paraglottic space involvement were followed up longitudinally for the effectiveness and timing of second look microsurgery. After initial transoral laser micro resection, all patients achieved microscopically clear resection margins. At second look microlaryngeal evaluation, local recurrence was found in four of 23 patients. Of these, two patients were salvaged by second look surgery and are disease free, whereas in two others, the larynx had to be subjected to open surgical intervention. One of two had extensive local recurrent tumor and underwent total laryngectomy with neck dissection followed by post-operative radiotherapy. Tracheohyoidopexy was done with successful functional and oncologic outcome for another patient who had local recurrence for the third time. Only the patient who underwent total laryngectomy with neck dissection was subjected to adjuvant post-operative radiotherapy. Finally, larynx was saved in 21 out of 23 patients.

Entities:  

Keywords:  Laryngeal cancer; Laser surgery; Microlaryngoscopy

Year:  2012        PMID: 23730573      PMCID: PMC3392354          DOI: 10.1007/s12070-012-0496-7

Source DB:  PubMed          Journal:  Indian J Otolaryngol Head Neck Surg        ISSN: 2231-3796


  22 in total

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Journal:  Ann Otol Rhinol Laryngol       Date:  1996-05       Impact factor: 1.547

2.  Transoral laser surgery for laryngeal cancer: outcome, complications and prognostic factors in 275 patients.

Authors:  S F Preuss; K Cramer; J P Klussmann; H E Eckel; O Guntinas-Lichius
Journal:  Eur J Surg Oncol       Date:  2008-02-20       Impact factor: 4.424

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Authors:  Y P Krespi; C J Meltzer
Journal:  Ann Otol Rhinol Laryngol       Date:  1989-02       Impact factor: 1.547

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Journal:  Laryngoscope       Date:  1972-12       Impact factor: 3.325

5.  Endoscopic laser surgery for early glottic carcinoma: a clinical and experimental study.

Authors:  M Wolfensberger; J C Dort
Journal:  Laryngoscope       Date:  1990-10       Impact factor: 3.325

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Journal:  Laryngoscope       Date:  1975-01       Impact factor: 3.325

7.  Prevention of anterior glottic stenosis after transoral microresection of glottic lesions involving the anterior commissure with mitomycin C.

Authors:  Jong-Lyel Roh; Yeo-Hoon Yoon
Journal:  Laryngoscope       Date:  2005-06       Impact factor: 3.325

8.  Endoscopic CO2 laser excision for tis, T1, and T2 glottic carcinomas: cure rate and prognostic factors.

Authors:  G Peretti; P Nicolai; L O Redaelli De Zinis; M Berlucchi; T Bazzana; F Bertoni; A R Antonelli
Journal:  Otolaryngol Head Neck Surg       Date:  2000-07       Impact factor: 3.497

9.  Transoral laser microresection for cancer of the larynx involving the anterior commissure.

Authors:  Bruce W Pearson; John R Salassa
Journal:  Laryngoscope       Date:  2003-07       Impact factor: 3.325

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Authors:  L Rucci; L Gammarota; M B Borghi Cirri
Journal:  Ann Otol Rhinol Laryngol       Date:  1996-04       Impact factor: 1.547

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  3 in total

Review 1.  Management of Early Glottic Cancer Treated by CO2 Laser According to Surgical-Margin Status: A Systematic Review of the Literature.

Authors:  Barbara Verro; Giuseppe Greco; Enzo Chianetta; Carmelo Saraniti
Journal:  Int Arch Otorhinolaryngol       Date:  2020-09-24

2.  Retrospective analysis of risk factors for lymph node metastasis in recurrent glottic cancer after primary laser surgery: a cohort study from China.

Authors:  Xuejun Chen; Junwei Huang; Shuo Ding; Gaofei Yin; Wen Gao; Yang Zhang; Zhigang Huang
Journal:  Ann Transl Med       Date:  2022-07

3.  Impact of resection margin status and revision transoral laser microsurgery in early glottic cancer: analysis of organ preservation and local disease control on a cohort of 153 patients.

Authors:  Carmelo Saraniti; Francesca Montana; Enzo Chianetta; Giuseppe Greco; Barbara Verro
Journal:  Braz J Otorhinolaryngol       Date:  2020-10-17
  3 in total

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