Literature DB >> 23730137

Recurrent unprovoked venous thromboembolism in a young female patient with high levels of homocysteine.

Ashish Anil Sule1, Tay Jam Chin, Lee Hwei Khien.   

Abstract

Hyperhomocysteinemia is a rare condition which predisposes to atherothrombosis. Recurrent venous thromboembolism (VTE) with hyperhomocysteinemia is known but extremely uncommon. Homocysteine levels of more than 22 umol/L can predispose to VTE in a middle-aged women. We describe a case of a middle-aged woman, community ambulant with recurrent VTE with intermediately high homocysteine levels. She had no other risk factors for recurrent venous thrombosis. In our article, we also discuss hyperhomocysteinemia and its link to VTE.

Entities:  

Keywords:  antifactor Xa; cardiovascular risk factors; deep vein thrombosis; factor V Leiden; hypertension; thrombophilia

Year:  2012        PMID: 23730137      PMCID: PMC3444009          DOI: 10.1055/s-0032-1315626

Source DB:  PubMed          Journal:  Int J Angiol        ISSN: 1061-1711


  21 in total

1.  The effect of a subnormal vitamin B-6 status on homocysteine metabolism.

Authors:  J B Ubbink; A van der Merwe; R Delport; R H Allen; S P Stabler; R Riezler; W J Vermaak
Journal:  J Clin Invest       Date:  1996-07-01       Impact factor: 14.808

2.  Cardiology patient pages. Homocysteine and MTHFR mutations: relation to thrombosis and coronary artery disease.

Authors:  Elizabeth A Varga; Amy C Sturm; Caron P Misita; Stephan Moll
Journal:  Circulation       Date:  2005-05-17       Impact factor: 29.690

Review 3.  Homocysteine and atherothrombosis.

Authors:  G N Welch; J Loscalzo
Journal:  N Engl J Med       Date:  1998-04-09       Impact factor: 91.245

4.  The mutation Ala677-->Val in the methylene tetrahydrofolate reductase gene: a risk factor for arterial disease and venous thrombosis.

Authors:  V R Arruda; P M von Zuben; L C Chiaparini; J M Annichino-Bizzacchi; F F Costa
Journal:  Thromb Haemost       Date:  1997-05       Impact factor: 5.249

5.  Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians.

Authors:  J Ma; M J Stampfer; C H Hennekens; P Frosst; J Selhub; J Horsford; M R Malinow; W C Willett; R Rozen
Journal:  Circulation       Date:  1996-11-15       Impact factor: 29.690

6.  Homocystinuria. I. A clinical and pathological study of nine subjects in six families.

Authors:  M C Carey; D E Donovan; O FitzGerald; F D McAuley
Journal:  Am J Med       Date:  1968-07       Impact factor: 4.965

7.  Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis.

Authors:  K S McCully
Journal:  Am J Pathol       Date:  1969-07       Impact factor: 4.307

8.  Methylenetetrahydrofolate reductase gene and coronary artery disease.

Authors:  F M van Bockxmeer; C D Mamotte; S D Vasikaran; R R Taylor
Journal:  Circulation       Date:  1997-01-07       Impact factor: 29.690

Review 9.  Homocysteine and thrombotic disease.

Authors:  A D'Angelo; J Selhub
Journal:  Blood       Date:  1997-07-01       Impact factor: 22.113

10.  Hyperhomocysteinemia as a risk factor for deep-vein thrombosis.

Authors:  M den Heijer; T Koster; H J Blom; G M Bos; E Briet; P H Reitsma; J P Vandenbroucke; F R Rosendaal
Journal:  N Engl J Med       Date:  1996-03-21       Impact factor: 91.245

View more
  6 in total

1.  A prospective study on hyperhomocysteinemia as an aggravating factor in chronic venous insufficiency.

Authors:  Maria Rotaru; Gabriela Mariana Iancu; Ioana Baldovin
Journal:  Exp Ther Med       Date:  2022-05-17       Impact factor: 2.751

2.  The effects of L-cysteine and N-acetyl-L-cysteine on homocysteine metabolism and haemostatic markers, and on cardiac and aortic histology in subchronically methionine-treated Wistar male rats.

Authors:  Sanja Kostić; Žarko Mićovic; Lazar Andrejević; Saša Cvetković; Aleksandra Stamenković; Sanja Stanković; Radmila Obrenović; Milica Labudović-Borović; Dragan Hrnčić; Vladimir Jakovljević; Dragan Djurić
Journal:  Mol Cell Biochem       Date:  2018-06-23       Impact factor: 3.396

3.  Study on relationships among deep vein thrombosis, homocysteine & related B group vitamins.

Authors:  Meral Ekim; Hasan Ekim; Yunus Keser Yilmaz; Bahadir Kulah; M Fevzi Polat; A Yesim Gocmen
Journal:  Pak J Med Sci       Date:  2015 Mar-Apr       Impact factor: 1.088

Review 4.  Role of hydrogen sulfide in endothelial dysfunction: Pathophysiology and therapeutic approaches.

Authors:  Valentina Citi; Alma Martelli; Era Gorica; Simone Brogi; Lara Testai; Vincenzo Calderone
Journal:  J Adv Res       Date:  2020-05-19       Impact factor: 10.479

5.  Effect of body weight on serum homocysteine level in patients with polycystic ovarian syndrome: A case control study.

Authors:  Ali I Al-Gareeb; Wafaa Salah Abd Al-Amieer; Hayder M Alkuraishy; Thabat J Al-Mayahi
Journal:  Int J Reprod Biomed (Yazd)       Date:  2016-02

6.  Venous thromboembolism and hyperhomocysteinemia as first manifestation of pernicious anemia: a case series.

Authors:  W Ammouri; Z Mezalek Tazi; H Harmouche; M Maamar; M Adnaoui
Journal:  J Med Case Rep       Date:  2017-09-02
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.