Literature DB >> 23730115

The development of scleromalacia after regional conjunctivectomy with the postoperative application of mitomycin C as an adjuvant therapy.

Hye Young Shin1, Man Soo Kim, Sung Kun Chung.   

Abstract

A 40-year-old woman presented with ocular discomfort in both eyes that had persisted for several months. Six months ago, she had undergone a bilateral nasal and temporal conjunctivectomy using a bare scleral technique followed by a postoperative application of 0.02% mitomycin C (MMC) to treat her chronic hyperemic conjunctiva for cosmesis. Slit-lamp examination revealed that the patient had bilateral nasal and temporal scleral thinning, and a calcified plaque on her nasal conjunctiva. There was no episcleral tissue present around the wound area, and it was difficult to detect any normal conjunctival tissue in the adjacent area for covering the lesion. We believe that performing an aggressive conjunctival excision procedure followed with MMC application for cosmetic enhancement may be disastrous in certain cases.

Entities:  

Keywords:  Mitomycin C; Regional conjunctivectomy; Scleromalacia

Mesh:

Substances:

Year:  2013        PMID: 23730115      PMCID: PMC3663065          DOI: 10.3341/kjo.2013.27.3.208

Source DB:  PubMed          Journal:  Korean J Ophthalmol        ISSN: 1011-8942


  6 in total

1.  Corneal melting after pterygium removal followed by topical mitomycin C therapy.

Authors:  D A Ewing-Chow; K G Romanchuk; G R Gilmour; J H Underhill; D B Climenhaga
Journal:  Can J Ophthalmol       Date:  1992-06       Impact factor: 1.882

2.  Scleral melting 16 years after pterygium excision with topical Mitomycin C adjuvant therapy.

Authors:  W M Wan Norliza; I Siti Raihan; J Azlyn Azwa; M Ibrahim
Journal:  Cont Lens Anterior Eye       Date:  2006-08-30       Impact factor: 3.077

3.  Successful treatment of necrotizing scleritis after conjunctival autografting for pterygium with amniotic membrane transplantation.

Authors:  Aylin Karalezli; Cem Kucukerdonmez; Mehmet Borazan; Yonca A Akova
Journal:  Orbit       Date:  2010-04

4.  Comeoscleral perforation after pterygium excision and intraoperative mitomycin C.

Authors:  Subhash Dadeya; Shibal Fatima
Journal:  Ophthalmic Surg Lasers Imaging       Date:  2003 Mar-Apr

5.  Trabeculectomy with mitomycin. A comparative study with fluorouracil.

Authors:  Y Kitazawa; K Kawase; H Matsushita; M Minobe
Journal:  Arch Ophthalmol       Date:  1991-12

6.  Limbal stem cell deficiency following topical mitomycin C treatment of conjunctival-corneal intraepithelial neoplasia.

Authors:  Blonie W Dudney; Monika A Malecha
Journal:  Am J Ophthalmol       Date:  2004-05       Impact factor: 5.258

  6 in total
  1 in total

Review 1.  Delayed manifestation of bilateral scleral thinning after I-BRITE(®) procedure and review of literature for cosmetic eye-whitening procedures.

Authors:  Majid Moshirfar; Michael V McCaughey; Carlton R Fenzl; Luis Santiago-Caban; Gregory D Kramer; Nick Mamalis
Journal:  Clin Ophthalmol       Date:  2015-03-04
  1 in total

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