Literature DB >> 23730072

OraVerse: Reverses Numbness After Dental Procedures.

J S Prasanna1.   

Abstract

The lingering numbness that can last anywhere from 3 to 5 h after a routine dental procedure is often an unnecessary, inconvenient hassle. Patients may find that their ability to speak, smile, eat and drink is impaired, and may even have uncontrollable drooling. The effects of local dental anesthetics can now be reversed. That's because OraVerse, an anesthetic reversal agent, can return the patient to normal sensation and function in about half the time. OraVerse which is U.S. Food and Drug Administration approved is a safe and effective form of phentolamine mesylate, a vasodilator that has been used in several other medical applications since 1952. OraVerse injection - the first and only proven safe and effective product of its kind can quickly reverse the effects of local dental anesthetics, so patient can carry on without impairment of talk, smile and drink after dental procedures. Studies also have shown that there are no known drug interactions and no evident toxicity or contraindications for using OraVerse.

Entities:  

Keywords:  Anaesthesia; OraVerse; Periodontal maintenance; Reverses numbness; Submucosal injection

Year:  2012        PMID: 23730072      PMCID: PMC3386412          DOI: 10.1007/s12663-011-0318-6

Source DB:  PubMed          Journal:  J Maxillofac Oral Surg        ISSN: 0972-8270


  18 in total

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Authors:  Stanley F Malamed
Journal:  Dent Today       Date:  2010-03

2.  New drugs on the horizon may improve the quality and safety of anesthesia.

Authors:  Joel M Weaver
Journal:  Anesth Prog       Date:  2008

3.  OraVerse helps you lose that numbing feeling.

Authors:  Thomas Morrow
Journal:  Manag Care       Date:  2008-09

4.  Phentolamine mesylate--an old medical drug becomes a new dental drug.

Authors:  Richard L Wynn
Journal:  Gen Dent       Date:  2009 May-Jun

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Authors:  L Gould; C V Reddy; W Chua; C R Swamy; J C Dorismond
Journal:  Br Heart J       Date:  1977-09

6.  Undiagnosed pheochromocytoma: the anesthesiologist nightmare.

Authors:  Duane J Myklejord
Journal:  Clin Med Res       Date:  2004-02

7.  Development of hibernomas in rats dosed with phentolamine mesylate during the 24-month carcinogenicity study.

Authors:  Frederique M Poulet; Mark R Berardi; William Halliwell; Barbara Hartman; Carol Auletta; Henry Bolte
Journal:  Toxicol Pathol       Date:  2004 Sep-Oct       Impact factor: 1.902

8.  Randomized study of phentolamine mesylate for reversal of local anesthesia.

Authors:  M Laviola; S K McGavin; G A Freer; G Plancich; S C Woodbury; S Marinkovich; R Morrison; A Reader; R B Rutherford; J A Yagiela
Journal:  J Dent Res       Date:  2008-07       Impact factor: 6.116

9.  Reversal of soft-tissue local anesthesia with phentolamine mesylate in adolescents and adults.

Authors:  Elliot V Hersh; Paul A Moore; Athena S Papas; J Max Goodson; Laura A Navalta; Siegfried Rogy; Bruce Rutherford; John A Yagiela
Journal:  J Am Dent Assoc       Date:  2008-08       Impact factor: 3.634

10.  Oral phentolamine mesylate in the treatment of complex regional pain syndrome.

Authors:  G J McCleane
Journal:  Ulster Med J       Date:  1996-05
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  3 in total

Review 1.  Basic pharmacology of local anaesthetics.

Authors:  A Taylor; G McLeod
Journal:  BJA Educ       Date:  2019-12-04

2.  Effect of a trial pharmaceutical solution on reversing sensations after using lidocain: An animal study.

Authors:  Abbas Haghighat; Amin Davoudi; Mohsen Minaiyan; Meghdad Molai; Abdolreza Afshar; Keyvan Basiri
Journal:  Anesth Essays Res       Date:  2015 Jan-Apr

3.  Efficacy of phentolamine mesylate in reducing the duration of various local anesthetics.

Authors:  Alejandro Gago-García; Cayetana Barrilero-Martin; Miguel Ángel Alobera-Gracia; Mariano Del Canto-Pingarrón; Jesús Seco-Calvo
Journal:  J Dent Anesth Pain Med       Date:  2021-01-29
  3 in total

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