BACKGROUND: The purpose of this study was to determine what quality of life (QOL) areas improve and deteriorate during the first year after total laryngectomy and to identify predictors of these changes. METHODS: One hundred seventy-four patients completed the European Organization for Research and Treatment of Cancer (EORTC) QOL questionnaires before laryngectomy, n = 133 before discharge from hospital, n = 110 at the end of rehabilitation, and n = 86 1 year after laryngectomy. Multivariate regression analysis was performed to estimate the effect of potential predictors on QOL. RESULTS: Areas that did not recover to baseline level were physical functioning, role functioning, social functioning, fatigue, dyspnea, appetite loss, financial difficulties, senses, speech, and social contact, whereas global health status, coughing, and weight improved. There was no evidence for predicting effects of age, sex, education, and tumor site. Tumor stage, recurrent disease, radiotherapy, and mental health did display predicting effects. Smoking status before the treatment had marginally significant effects. CONCLUSION: QOL decreases initially after laryngectomy; some QOL areas recover slowly over the course of the year after surgery, and some remain significantly worse than at baseline.
BACKGROUND: The purpose of this study was to determine what quality of life (QOL) areas improve and deteriorate during the first year after total laryngectomy and to identify predictors of these changes. METHODS: One hundred seventy-four patients completed the European Organization for Research and Treatment of Cancer (EORTC) QOL questionnaires before laryngectomy, n = 133 before discharge from hospital, n = 110 at the end of rehabilitation, and n = 86 1 year after laryngectomy. Multivariate regression analysis was performed to estimate the effect of potential predictors on QOL. RESULTS: Areas that did not recover to baseline level were physical functioning, role functioning, social functioning, fatigue, dyspnea, appetite loss, financial difficulties, senses, speech, and social contact, whereas global health status, coughing, and weight improved. There was no evidence for predicting effects of age, sex, education, and tumor site. Tumor stage, recurrent disease, radiotherapy, and mental health did display predicting effects. Smoking status before the treatment had marginally significant effects. CONCLUSION: QOL decreases initially after laryngectomy; some QOL areas recover slowly over the course of the year after surgery, and some remain significantly worse than at baseline.
Authors: A Meyer; J Keszte; D Wollbrück; A Dietz; J Oeken; H J Vogel; S Koscielny; K Breitenstein; E F Meister; F Pabst; J Schock; S Bourkas; S Singer Journal: Support Care Cancer Date: 2014-10-25 Impact factor: 3.603
Authors: Ximena Mimica; Martin Hanson; Snehal G Patel; Marlena McGill; Sean McBride; Nancy Lee; Lara A Dunn; Jennifer R Cracchiolo; Jatin P Shah; Richard J Wong; Ian Ganly; Marc A Cohen Journal: Head Neck Date: 2019-08-21 Impact factor: 3.147
Authors: Stacey M Davidson; Huasing C Ko; Paul M Harari; Aaron M Wieland; Shuai Chen; Andrew M Baschnagel; Randall J Kimple; Matthew E Witek Journal: Otolaryngol Head Neck Surg Date: 2018-04-03 Impact factor: 3.497
Authors: Femke Jansen; Ingrid C Cnossen; Simone E J Eerenstein; Veerle M H Coupé; Birgit I Witte; Cornelia F van Uden-Kraan; Patricia Doornaert; Weibel W Braunius; Remco De Bree; José A U Hardillo; Jimmie Honings; György B Halmos; C René Leemans; Irma M Verdonck-de Leeuw Journal: BMC Cancer Date: 2016-08-02 Impact factor: 4.430
Authors: Ingrid C Cnossen; Cornelia F van Uden-Kraan; Simone E J Eerenstein; Femke Jansen; Birgit I Witte; Martin Lacko; José A Hardillo; Jimmie Honings; Gyorgy B Halmos; Noortje L Q Goedhart-Schwandt; Remco de Bree; C René Leemans; Irma M Verdonck-de Leeuw Journal: Support Care Cancer Date: 2015-08-26 Impact factor: 3.603