Literature DB >> 2372855

Occurrence of gastroesophageal reflux on induction of anaesthesia does not correlate with the volume of gastric contents.

J F Hardy1, Y Lepage, N Bonneville-Chouinard.   

Abstract

In an attempt to explain the discrepancy between the high number of patients said to be at risk of aspiration pneumonitis and the low reported incidence of this anaesthetic complication, 100 ASA physical status I-II elective surgical patients were studied. The volume of fluid present in the stomach at the time of induction of anaesthesia was correlated with gastroesophageal reflux (GER) detected by visual inspection of the pharynx and by continuous measurement of upper oesophageal pH. Mean gastric volume was 30 +/- 28 ml (range 0-210 ml). Gastric fluid volume greater than or equal to 0.4 ml.kg-1 at pH less than or equal to 2.5 was present in 46 patients. No GER was detected during induction of anaesthesia in our sample of 100 patients. Furthermore, patient age, duration of preoperative fasting, body mass index, cigarette smoking, alcohol consumption, preoperative anxiety, and a history of preoperative GER were not correlated with significant modifications of gastric volume or pH. We conclude that the low incidence of aspiration pneumonitis in elective surgical patients may be explained in part by the very low risk of GER, despite gastric fluid volumes of more than 0.4 ml.kg-1 in a high proportion of this patient population.

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Year:  1990        PMID: 2372855     DOI: 10.1007/BF03006316

Source DB:  PubMed          Journal:  Can J Anaesth        ISSN: 0832-610X            Impact factor:   5.063


  27 in total

1.  Gastric volume and pH in out-patients.

Authors:  B Y Ong; R J Palahniuk; M Cumming
Journal:  Can Anaesth Soc J       Date:  1978-01

2.  Induction of gastro-oesophageal reflux by alcohol.

Authors:  S E Kaufman; M D Kaye
Journal:  Gut       Date:  1978-04       Impact factor: 23.059

3.  Volume and pH of gastric juice in obese patients.

Authors:  R W Vaughan; S Bauer; L Wise
Journal:  Anesthesiology       Date:  1975-12       Impact factor: 7.892

4.  Pulmonary effects of experimental graded aspiration of hydrochloric acid.

Authors:  L J Greenfield; R P Singleton; D R McCaffree; J J Coalson
Journal:  Ann Surg       Date:  1969-07       Impact factor: 12.969

5.  The symptom index: a clinically important parameter of ambulatory 24-hour esophageal pH monitoring.

Authors:  G J Wiener; J E Richter; J B Copper; W C Wu; D O Castell
Journal:  Am J Gastroenterol       Date:  1988-04       Impact factor: 10.864

6.  Assessment of risk factors related to the acid aspiration syndrome in pediatric patients-gastric ph and residual volume.

Authors:  C J Coté; N G Goudsouzian; L M Liu; D F Dedrick; S K Szyfelbein
Journal:  Anesthesiology       Date:  1982-01       Impact factor: 7.892

7.  Gastric fluid volume and pH after fentanyl, enflurane, or halothane-nitrous oxide anesthesia with or without atropine or glycopyrrolate.

Authors:  R K Stoelting
Journal:  Anesth Analg       Date:  1980-04       Impact factor: 5.108

8.  A survey of 112,000 anaesthetics at one teaching hospital (1975-83).

Authors:  M M Cohen; P G Duncan; W D Pope; C Wolkenstein
Journal:  Can Anaesth Soc J       Date:  1986-01

9.  The pulmonary consequences of aspiration of gastric contents at pH values greater than 2.5.

Authors:  D J Schwartz; J W Wynne; C P Gibbs; C I Hood; E J Kuck
Journal:  Am Rev Respir Dis       Date:  1980-01

10.  Aspiration during anaesthesia: a computer-aided study of 185,358 anaesthetics.

Authors:  G L Olsson; B Hallen; K Hambraeus-Jonzon
Journal:  Acta Anaesthesiol Scand       Date:  1986-01       Impact factor: 2.105

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  4 in total

1.  Gastroesophageal reflux during anaesthesia.

Authors:  L Illing; P G Duncan; R Yip
Journal:  Can J Anaesth       Date:  1992-05       Impact factor: 5.063

2.  Does ranitidine provide protection against acid gastroesophageal reflux?

Authors:  D Verbessem; F Camu; A Van de Velde
Journal:  Can J Anaesth       Date:  1993-01       Impact factor: 5.063

Review 3.  Factors Affecting Intraoperative Gastro-Oesophageal Reflux in Dogs and Cats.

Authors:  Ioannis Savvas; Kiriaki Pavlidou; Tilemachos Anagnostou; Eugenia Flouraki; George Kazakos; Dimitrios Raptopoulos
Journal:  Animals (Basel)       Date:  2022-01-20       Impact factor: 2.752

Review 4.  Pre-operative respiratory evaluation and management of patients for upper abdominal surgery.

Authors:  J M Davies
Journal:  Yale J Biol Med       Date:  1991 Jul-Aug
  4 in total

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