| Literature DB >> 23728353 |
Muneer Ahmad Dar1, Adil Mehraj Khan, Rajinder Raina, Pawan Kumar Verma, Mudasir Sultana.
Abstract
The oxidative stress-inducing potential of the pyrethroid insecticide, bifenthrin, was evaluated in rats at 5.8 mg/kg body weight once daily for 20 or 30 days. Bifenthrin treated animals showed significantly increased lipid peroxidation, evidenced by increased blood malondialdehyde levels. Blood glutathione levels and activities of catalase and glutathione peroxidase decreased significantly in the bifenthrin treated animals after both 20 and 30 days of treatment, whereas, the activities of superoxide dismutase and glutathione S-transferase decreased significantly only on the 30th day. In conclusion, bifenthrin has a potential to induce severe oxidative stress in rats exposed to sublethal concentrations.Entities:
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Year: 2013 PMID: 23728353 DOI: 10.1007/s00128-013-1022-7
Source DB: PubMed Journal: Bull Environ Contam Toxicol ISSN: 0007-4861 Impact factor: 2.151