| Literature DB >> 23727306 |
Veronika Lukacs-Kornek1, Detlef Schuppan.
Abstract
The phenotype and function of liver dendritic cells (LDCs) are poorly understood. This Snapshot summarizes our current knowledge on LDCs in the healthy and injured liver, and their role in fibrosis progression and reversal. It also draws attention to various pitfalls in the current experimental design and conclusions based on available data.Entities:
Keywords: APC; BDL; BM; Batf3; CCL(4); CD11c-DTR; CTL; DCs; DT; DTR; ECM; FA; FMS-like tyrosine kinase 3 ligand; Flt3L; GM-CSF; HL-LDC; HSC; IL-6; Id2; LDC; LL-LDC; LPS; Liver dendritic cells; MCD; MCP-1; MMP-9; MMP13; NASH; PAMPs; PBMC; TAA; TNFα; Tolerance; antigen presenting cell; basic leucine zipper transcription factor, ATF-like 3; bile duct ligation; bone marrow; carbon tetrachloride; cytotoxic T lymphocyte; dendritic cells; diphtheria toxin; diphtheria toxin receptor; extracellular matrix; fatty acid; granulocyte macrophage colony-stimulating factor; hepatic stellate cells; high-lipid liver dendritic cell; inhibitor of DNA binding 2; interleukin-6; lipopolysaccharide; liver dendritic cell; low-lipid liver dendritic cell; matrix metalloproteinase-13; matrix metalloproteinase-9; methionine choline deficient; monocyte chemotactic protein-1; non-alcoholic steatohepatitis; pDC; pathogen-associated molecular patterns; peripheral blood mononuclear cells; plasmacytoid dendritic cell; thioacetamide; tumor necrosis factor-alpha; zbtb46; zinc finger and BTB domain containing 46
Mesh：
Year: 2013 PMID： 23727306 DOI： 10.1016/j.jhep.2013.05.033
Source DB: PubMed Journal: J Hepatol ISSN： 0168-8278 Impact factor: 25.083