Literature DB >> 2372600

Control of defecation in patients with spinal injuries by stimulation of sacral anterior nerve roots.

R P MacDonagh1, W M Sun, R Smallwood, D Forster, N W Read.   

Abstract

OBJECTIVE: To observe the effects of stimulation of the sacral anterior roots on anorectal and low colonic pressures and to programme implanted stimulators to produce defecation.
DESIGN: Prospective study of 12 consecutive patients.
SETTING: Spinal injuries unit and university gastrointestinal physiology department. PATIENTS: 12 Patients with complete supraconal spinal cord lesions. Their injuries had been sustained at least two years before the study.
INTERVENTIONS: A Brindley-Finetech intradural sacral anterior root stimulator was implanted in all patients. Three months postoperatively the stimulator settings were adjusted after measurement of simultaneous anorectal and low colonic pressures. MAIN OUTCOME MEASURES: Full defecation.
RESULTS: Six patients achieved complete rectal evacuation of faeces using the implant and subsequently did not require manual help for defecation. For all but one of the patients the total time taken to complete defecation was reduced, and all were free from constipation, the most prevalent gastrointestinal symptom in patients with spinal injuries.
CONCLUSIONS: Sacral anterior root stimulators can be programmed to achieve complete unassisted defecation and can considerably improve the quality of life of patients with spinal injuries.

Entities:  

Mesh:

Year:  1990        PMID: 2372600      PMCID: PMC1663181          DOI: 10.1136/bmj.300.6738.1494

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  19 in total

1.  Microprocessor-controlled colonic peristalsis: dynamic parametric modeling in dogs.

Authors:  Peter Z Rashev; Manuel Amaris; Kenneth L Bowes; Martin P Mintchev
Journal:  Dig Dis Sci       Date:  2002-05       Impact factor: 3.199

2.  Colonic electrical stimulation regulates colonic transit via the nitrergic pathway in rats.

Authors:  Shi Liu; J D Z Chen
Journal:  Dig Dis Sci       Date:  2006-03       Impact factor: 3.199

Review 3.  Neurogenic bowel management after spinal cord injury: a systematic review of the evidence.

Authors:  A Krassioukov; J J Eng; G Claxton; B M Sakakibara; S Shum
Journal:  Spinal Cord       Date:  2010-03-09       Impact factor: 2.772

4.  Increased vaginal blood flow induced by implant electrical stimulation of sacral anterior roots in the conscious woman: a case study.

Authors:  R J Levin; R P Macdonagh
Journal:  Arch Sex Behav       Date:  1993-10

5.  Sacral neuromodulation for the management of severe constipation: development of a constipation treatment protocol.

Authors:  Abhiram Sharma; Ben Liu; Philip Waudby; Graeme S Duthie
Journal:  Int J Colorectal Dis       Date:  2011-06-30       Impact factor: 2.571

6.  Sacral anterior root stimulated defecation in spinal cord injuries: an experimental study in canine model.

Authors:  Shi-Min Chang; Guang-Rong Yu; Ying-Min Diao; Meng-Jie Zhang; Shi-Bo Wang; Chun-Lin Hou
Journal:  World J Gastroenterol       Date:  2005-03-21       Impact factor: 5.742

Review 7.  Slow transit constipation: a disorder of pelvic autonomic nerves?

Authors:  C H Knowles; S M Scott; P J Lunniss
Journal:  Dig Dis Sci       Date:  2001-02       Impact factor: 3.199

8.  Anorectal function in patients with complete supraconal spinal cord lesions.

Authors:  R MacDonagh; W M Sun; D G Thomas; R Smallwood; N W Read
Journal:  Gut       Date:  1992-11       Impact factor: 23.059

9.  Autonomic influences on colorectal motility and pelvic surgery.

Authors:  J S Varma
Journal:  World J Surg       Date:  1992 Sep-Oct       Impact factor: 3.352

Review 10.  Recent update on basic mechanisms of spinal cord injury.

Authors:  Syed A Quadri; Mudassir Farooqui; Asad Ikram; Atif Zafar; Muhammad Adnan Khan; Sajid S Suriya; Chad F Claus; Brian Fiani; Mohammed Rahman; Anirudh Ramachandran; Ian I T Armstrong; Muhammad A Taqi; Martin M Mortazavi
Journal:  Neurosurg Rev       Date:  2018-07-11       Impact factor: 3.042

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