| Literature DB >> 23725760 |
Andrew P McMahon1, Sean M Hasso.
Abstract
Reporting in Nature, Sanders et al. (2013) implicate filopodial projections in Sonic hedgehog (Shh) patterning of the limb. Actin-based filopodia transport Shh from producing cells, while filopodia of responding cells bear Cdon and Boc: coreceptors in the Shh pathway. These findings suggest a new mechanism of ligand movement and transmission.Entities:
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Year: 2013 PMID: 23725760 DOI: 10.1016/j.devcel.2013.05.008
Source DB: PubMed Journal: Dev Cell ISSN: 1534-5807 Impact factor: 12.270