Literature DB >> 2372251

Intranasal immunization of mice with recombinant protein antigen of serotype c Streptococcus mutans and cholera toxin B subunit.

I Takahashi1, N Okahashi, T Kanamoto, H Asakawa, T Koga.   

Abstract

The cholera toxin subunit and the recombinant cell-surface antigen (molecular mass of 190,000 Da) were administered intranasally to BALB/c mice. After 30 days, the mice were immunized intranasally with the recombinant protein antigen alone. High serum IgG and salivary IgA responses to the protein antigen were induced by the intranasal immunization.

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Year:  1990        PMID： 2372251     DOI： 10.1016/0003-9969(90)90211-r

Source DB:  PubMed          Journal:  Arch Oral Biol        ISSN： 0003-9969            Impact factor:   2.633


  11 in total

1.  Intranasal immunization against dental caries with a Streptococcus mutans-enriched fimbrial preparation.

Authors:  M Fontana; A J Dunipace; G K Stookey; R L Gregory
Journal:  Clin Diagn Lab Immunol       Date:  1999-05

2.  Distribution, persistence, and recall of serum and salivary antibody responses to peroral immunization with protein antigen I/II of Streptococcus mutans coupled to the cholera toxin B subunit.

Authors:  M W Russell; H Y Wu
Journal:  Infect Immun       Date:  1991-11       Impact factor: 3.441

3.  Adjuvant activity of monophosphoryl lipid A for nasal and oral immunization with soluble or liposome-associated antigen.

Authors:  N K Childers; K L Miller; G Tong; J C Llarena; T Greenway; J T Ulrich; S M Michalek
Journal:  Infect Immun       Date:  2000-10       Impact factor: 3.441

4.  A controlled clinical study of the effect of nasal immunization with a Streptococcus mutans antigen alone or incorporated into liposomes on induction of immune responses.

Authors:  N K Childers; G Tong; S Mitchell; K Kirk; M W Russell; S M Michalek
Journal:  Infect Immun       Date:  1999-02       Impact factor: 3.441

5.  Induction of antibody-secreting cells and T-helper and memory cells in murine nasal lymphoid tissue.

Authors:  H Y Wu; E B Nikolova; K W Beagley; M W Russell
Journal:  Immunology       Date:  1996-08       Impact factor: 7.397

6.  Induction of mucosal immunity by intranasal application of a streptococcal surface protein antigen with the cholera toxin B subunit.

Authors:  H Y Wu; M W Russell
Journal:  Infect Immun       Date:  1993-01       Impact factor: 3.441

7.  Salivary, nasal, genital, and systemic antibody responses in monkeys immunized intranasally with a bacterial protein antigen and the Cholera toxin B subunit.

Authors:  M W Russell; Z Moldoveanu; P L White; G J Sibert; J Mestecky; M Michalek S
Journal:  Infect Immun       Date:  1996-04       Impact factor: 3.441

8.  Development of antibody-secreting cells and antigen-specific T cells in cervical lymph nodes after intranasal immunization.

Authors:  H Y Wu; E B Nikolova; K W Beagley; J H Eldridge; M W Russell
Journal:  Infect Immun       Date:  1997-01       Impact factor: 3.441

9.  Genetic control of immune responses in mice to synthetic peptides of a Streptococcus mutans surface protein antigen.

Authors:  I Takahashi; K Matsushita; T Nisizawa; N Okahashi; M W Russell; Y Suzuki; E Munekata; T Koga
Journal:  Infect Immun       Date:  1992-02       Impact factor: 3.441

10.  Protective salivary immunoglobulin A responses against Streptococcus mutans infection after intranasal immunization with S. mutans antigen I/II coupled to the B subunit of cholera toxin.

Authors:  J Katz; C C Harmon; G P Buckner; G J Richardson; M W Russell; S M Michalek
Journal:  Infect Immun       Date:  1993-05       Impact factor: 3.441
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