Major hepatic resections: a 10-year experience with emphasis on special problems.

From 1976-1985, 32 patients underwent major hepatic resection at the University of Mississippi Medical Center. This experience was reviewed to determine the relationship of blood loss, postoperative hyperbilirubinemia, and the performance of concomitant surgical procedures to operative mortality, local tumor recurrence, and long-term survival. There were no deaths among 16 elective resections. Of 16 patients undergoing emergency resections, seven died (43.8%). The mortality rate correlated strongly with intraoperative transfusion of more than 10 units of blood and with postoperative hyperbilirubinemia. Performance of additional procedures increased mortality significantly after emergency, but not elective, hepatic resection. Median survival was 53.4 months in patients resected for hepatoma and 33.5 months in those patients resected for metastatic colon lesions. Local recurrence in a patient with hepatoma was managed by resection at 13 months, with no evidence of further recurrence at 69 months.