Literature DB >> 23719236

Falls in HIV-infected patients: a geriatric syndrome in a susceptible population.

Marco Andres Ruiz1, Tom Reske, Charles Cefalu, John Estrada.   

Abstract

BACKGROUND: Falls is a common geriatric syndrome that has not been well characterized in HIV-infected populations.
METHODS: We retrospectively reviewed our database and identified patients who fell over the last 12 months.
RESULTS: Thirty-two patients were identified (incidence rate of 16 × 1000 patients per year). Twenty-five percent were female and 75% male. Sixty-seven percent were African American with 33% Caucasians. Average age was 48.19, number of years with HIV infection on average was 9.38 years, mean CD4 count 347.2 cell/mm(3), mean HIV viral load was 31 379 copies/mL. The average number of medications was 8.7 with a mean of 3.48 comorbidities. The mean vitamin D level was 27.20. Sixty-two percent of patients were compliant with antiretroviral therapy. Univariate and multivariate analysis showed that number of medications (< .005 medications; P < .005), more than 3 comorbidities (P < .005), and noncompliance (P < .001) were related to falls in this population.
CONCLUSION: Falls is a common geriatric syndrome. Associated risk factors in our cohort included number of medications, more than 3 comorbidities, and noncompliance. Larger studies are needed to properly characterize this geriatric syndrome in HIV-infected patients. As HIV-infected populations age, a shift into a more comprehensive geriatrics care including fall risk evaluation may be needed.

Entities:  

Keywords:  HIV; elderly; falls

Mesh:

Substances:

Year:  2013        PMID: 23719236     DOI: 10.1177/2325957413488204

Source DB:  PubMed          Journal:  J Int Assoc Provid AIDS Care        ISSN: 2325-9574


  13 in total

Review 1.  Assessment of geriatric syndromes and physical function in people living with HIV.

Authors:  Meredith Greene; Amy C Justice; Kenneth E Covinsky
Journal:  Virulence       Date:  2016-10-07       Impact factor: 5.882

2.  Polypharmacy, Hazardous Alcohol and Illicit Substance Use, and Serious Falls Among PLWH and Uninfected Comparators.

Authors:  Julie A Womack; Terrence E Murphy; Christopher T Rentsch; Janet P Tate; Harini Bathulapalli; Alexandria C Smith; Jonathan Bates; Samah Jarad; Cynthia L Gibert; Maria C Rodriguez-Barradas; Phyllis C Tien; Michael T Yin; Thomas M Gill; Gary Friedlaender; Cynthia A Brandt; Amy C Justice
Journal:  J Acquir Immune Defic Syndr       Date:  2019-11-01       Impact factor: 3.731

3.  Gait and Balance Biomechanics in Older Adults With and Without Human Immunodeficiency Virus.

Authors:  Alice S Ryan; Anindo Roy; Krisann K Oursler
Journal:  AIDS Res Hum Retroviruses       Date:  2019 Nov/Dec       Impact factor: 2.205

4.  Frailty is strongly associated with increased risk of recurrent falls among older HIV-infected adults.

Authors:  Katherine Tassiopoulos; Mona Abdo; Kunling Wu; Susan L Koletar; Frank J Palella; Robert Kalayjian; Babafemi Taiwo; Kristine M Erlandson
Journal:  AIDS       Date:  2017-10-23       Impact factor: 4.177

Review 5.  More than osteoporosis: age-specific issues in bone health.

Authors:  Kristine M Erlandson; Giovanni Guaraldi; Julian Falutz
Journal:  Curr Opin HIV AIDS       Date:  2016-05       Impact factor: 4.283

6.  Falls among middle-aged women in the Women's Interagency HIV Study.

Authors:  Anjali Sharma; Donald R Hoover; Qiuhu Shi; Susan Holman; Michael W Plankey; Amber L Wheeler; Kathleen Weber; Michelle Floris-Moore; Hector H Bolivar; David E Vance; Wendy J Mack; Elizabeth T Golub; Marcia McDonnell Holstad; Michael T Yin
Journal:  Antivir Ther       Date:  2016-07-18

Review 7.  Inflammation Strikes Again: Frailty and HIV.

Authors:  Stephanie M Fukui; Damani A Piggott; Kristine M Erlandson
Journal:  Curr HIV/AIDS Rep       Date:  2018-02       Impact factor: 5.071

8.  Polypharmacy among HIV positive older adults on anti-retroviral therapy attending an urban clinic in Uganda.

Authors:  Michael Ssonko; Fiona Stanaway; Harriet K Mayanja; Tabitha Namuleme; Robert Cumming; John L Kyalimpa; Yvonne Karamagi; Barbara Mukasa; Vasi Naganathan
Journal:  BMC Geriatr       Date:  2018-05-29       Impact factor: 3.921

Review 9.  Effects of drug pharmacokinetic/pharmacodynamic properties, characteristics of medication use, and relevant pharmacological interventions on fall risk in elderly patients.

Authors:  Ying Chen; Ling-Ling Zhu; Quan Zhou
Journal:  Ther Clin Risk Manag       Date:  2014-06-13       Impact factor: 2.423

Review 10.  Objective impairments of gait and balance in adults living with HIV-1 infection: a systematic review and meta-analysis of observational studies.

Authors:  Karina Berner; Linzette Morris; Jochen Baumeister; Quinette Louw
Journal:  BMC Musculoskelet Disord       Date:  2017-08-01       Impact factor: 2.362

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