Literature DB >> 2371833

Neuroendocrine differentiation in a case of acinic cell carcinoma of the parotid gland.

K Ito1, K Kakudo, I Mori, M Horiuchi, Y Osamura.   

Abstract

We report a case of acinic cell carcinoma of the parotid gland with neuroendocrine differentiation. Light microscopically, the tumor appeared as clear cell-type acinic cell carcinoma. In addition, the tumor showed neurosecretory features such as Grimelius positivity and the presence of neurosecretory granules by electron microscopy. We suggest that a tumor cell arising from a stem cell can show simultaneous differentiation to both neuroendocrine and acinic cells.

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Year:  1990        PMID： 2371833     DOI： 10.1111/j.1440-1827.1990.tb01562.x

Source DB:  PubMed          Journal:  Acta Pathol Jpn        ISSN： 0001-6632


  3 in total

1.  Undifferentiated carcinoma of parotid gland.

Authors:  J I López; J Alfaro; C Ballestin
Journal:  J Clin Pathol       Date:  1991-05       Impact factor: 3.411

Review 2.  Salivary acinic cell carcinoma: reappraisal and update.

Authors:  V Vander Poorten; A Triantafyllou; L D R Thompson; J Bishop; E Hauben; J Hunt; A Skalova; G Stenman; R P Takes; D R Gnepp; H Hellquist; B Wenig; D Bell; A Rinaldo; A Ferlito
Journal:  Eur Arch Otorhinolaryngol       Date:  2015-12-19       Impact factor: 2.503

3.  Acinic cell carcinoma with extensive neuroendocrine differentiation: a diagnostic challenge.

Authors:  Somak Roy; Kajal Kiran Dhingra; Parul Gupta; Nita Khurana; Bulbul Gupta; Ravi Meher
Journal:  Head Neck Pathol       Date:  2009-03-26
  3 in total

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