Literature DB >> 2371783

The hemagglutinating glycoproteins of influenza B and C viruses are acylated with different fatty acids.

M Veit1, G Herrler, M F Schmidt, R Rott, H D Klenk.   

Abstract

We present evidence that the hemagglutinin (HA) of influenza B virus and the glycoprotein of influenza C virus (HEF) are acylated. The fatty acid linkage is sensitive to treatment with hydroxylamine and mercaptoethanol, which points to a labile thioester-type linkage. The HA of influenza B virus contains mainly palmitic acid, whereas the HEF glycoprotein of influenza C virus is acylated with stearic acid which has not been observed before as the prevailing fatty acid in viral or cellular acyl proteins.

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Year:  1990        PMID： 2371783     DOI： 10.1016/0042-6822(90)90554-5

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  14 in total

1.  Characterization of a second protein (CM2) encoded by RNA segment 6 of influenza C virus.

Authors:  S Hongo; K Sugawara; Y Muraki; F Kitame; K Nakamura
Journal:  J Virol       Date:  1997-04       Impact factor: 5.103

2.  Influenza virus assembly and lipid raft microdomains: a role for the cytoplasmic tails of the spike glycoproteins.

Authors:  J Zhang; A Pekosz; R A Lamb
Journal:  J Virol       Date:  2000-05       Impact factor: 5.103

3.  Site-specific S-acylation of influenza virus hemagglutinin: the location of the acylation site relative to the membrane border is the decisive factor for attachment of stearate.

Authors:  Katharina Brett; Larisa V Kordyukova; Marina V Serebryakova; Ramil R Mintaev; Andrei V Alexeevski; Michael Veit
Journal:  J Biol Chem       Date:  2014-10-27       Impact factor: 5.157

4.  Cytoplasmic tail length influences fatty acid selection for acylation of viral glycoproteins.

Authors:  M Veit; H Reverey; M F Schmidt
Journal:  Biochem J       Date:  1996-08-15       Impact factor: 3.857

5.  Site-specific mutagenesis identifies three cysteine residues in the cytoplasmic tail as acylation sites of influenza virus hemagglutinin.

Authors:  M Veit; E Kretzschmar; K Kuroda; W Garten; M F Schmidt; H D Klenk; R Rott
Journal:  J Virol       Date:  1991-05       Impact factor: 5.103

6.  Influence of acylation sites of influenza B virus hemagglutinin on fusion pore formation and dilation.

Authors:  Makoto Ujike; Katsuhisa Nakajima; Eri Nobusawa
Journal:  J Virol       Date:  2004-11       Impact factor: 5.103

7.  A seven-segmented influenza A virus expressing the influenza C virus glycoprotein HEF.

Authors:  Qinshan Gao; Edward W A Brydon; Peter Palese
Journal:  J Virol       Date:  2008-04-30       Impact factor: 5.103

8.  S acylation of the hemagglutinin of influenza viruses: mass spectrometry reveals site-specific attachment of stearic acid to a transmembrane cysteine.

Authors:  Larisa V Kordyukova; Marina V Serebryakova; Ludmila A Baratova; Michael Veit
Journal:  J Virol       Date:  2008-07-02       Impact factor: 5.103

9.  Amantadine inhibits an early, M2 protein-dependent event in the replication cycle of avian influenza (H7) viruses.

Authors:  A P Kendal; H D Klenk
Journal:  Arch Virol       Date:  1991       Impact factor: 2.574

Review 10.  Hemagglutinin-esterase-fusion (HEF) protein of influenza C virus.

Authors:  Mingyang Wang; Michael Veit
Journal:  Protein Cell       Date:  2015-07-28       Impact factor: 14.870
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