Literature DB >> 23717343

Factors Affecting Sustained Medication Adherence and Its Impact on Health Care Utilization in Patients with Diabetes.

Deborah Taira Juarez1, Candace Tan, James Davis, Marjorie Mau.   

Abstract

OBJECTIVE: To identify factors associated with years of medication adherence and to examine the relationship between years of adherence and health care utilization.
METHODS: This retrospective analysis used administrative data from adult patients with diabetes enrolled in health plan in Hawaii for four years (n= 23,450 patients). Ordered logistic regression was used to examine factors related to years of medication adherence for three types of medications (anti-diabetic, antihypertensive, lipid-lowering). Multivariable logistic regression and negative binomial regression were used to examine relationship between years of adherence and health care utilization (hospitalizations and emergency department visits). KEY
FINDINGS: Adherence to any of the medications for all four years was significantly associated with lower odds of a hospitalization or emergency department visit in the third year. The magnitude of reduction in utilization was greater for adherence to anti-diabetic and lipid-lowering medications, at 31% compared to 22% for antihypertensives. The 9% of patients who were adherent to all three types of medications for all four years showed a reduction of 53%.
CONCLUSIONS: Improvement is needed in medication adherence across all three types of medication. Interventions may need to target younger adults, women, patients with congestive heart failure, Filipinos and Native Hawaiians.

Entities:  

Keywords:  Medication adherence; health care utilization; health disparities

Year:  2013        PMID: 23717343      PMCID: PMC3664067          DOI: 10.1111/jphs.12016

Source DB:  PubMed          Journal:  J Pharm Health Serv Res        ISSN: 1759-8885


  18 in total

Review 1.  Adherence to medication.

Authors:  Lars Osterberg; Terrence Blaschke
Journal:  N Engl J Med       Date:  2005-08-04       Impact factor: 91.245

2.  Prescription co-pay reduction program for diabetic employees.

Authors:  Kavita V Nair; Kerri Miller; Jinhee Park; Richard R Allen; Joseph J Saseen; Vinita Biddle
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3.  Five Ms of adherence.

Authors:  Zachary Bloomgarden; Sam Dagogo-Jack
Journal:  J Diabetes       Date:  2011-09       Impact factor: 4.006

Review 4.  Patient adherence to medication requirements for therapy of type 2 diabetes.

Authors:  C J Bailey; M Kodack
Journal:  Int J Clin Pract       Date:  2011-03       Impact factor: 2.503

5.  Relationship of oral antihyperglycemic (sulfonylurea or metformin) medication adherence and hemoglobin A1c goal attainment for HMO patients enrolled in a diabetes disease management program.

Authors:  David B Lawrence; Kelly R Ragucci; Laura B Long; Beth S Parris; Lisa A Helfer
Journal:  J Manag Care Pharm       Date:  2006 Jul-Aug

6.  Effect of medication nonadherence on hospitalization and mortality among patients with diabetes mellitus.

Authors:  P Michael Ho; John S Rumsfeld; Frederick A Masoudi; David L McClure; Mary E Plomondon; John F Steiner; David J Magid
Journal:  Arch Intern Med       Date:  2006-09-25

7.  Persistent use of secondary preventive drugs declines rapidly during the first 2 years after stroke.

Authors:  Eva-Lotta Glader; Maria Sjölander; Marie Eriksson; Michael Lundberg
Journal:  Stroke       Date:  2010-01-14       Impact factor: 7.914

Review 8.  Interventions for enhancing medication adherence.

Authors:  R B Haynes; E Ackloo; N Sahota; H P McDonald; X Yao
Journal:  Cochrane Database Syst Rev       Date:  2008-04-16

9.  Comparison of drug adherence rates among patients with seven different medical conditions.

Authors:  Becky A Briesacher; Susan E Andrade; Hassan Fouayzi; K Arnold Chan
Journal:  Pharmacotherapy       Date:  2008-04       Impact factor: 4.705

Review 10.  Lipid management in the prevention of stroke: review and updated meta-analysis of statins for stroke prevention.

Authors:  Pierre Amarenco; Julien Labreuche
Journal:  Lancet Neurol       Date:  2009-05       Impact factor: 44.182

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  19 in total

1.  Getting less of what you want: reductions in statistical power and increased bias when categorizing medication adherence data.

Authors:  Stephen J Tueller; Pascal R Deboeck; Richard A Van Dorn
Journal:  J Behav Med       Date:  2016-02-27

2.  Failure to reach target glycated a1c levels among patients with diabetes who are adherent to their antidiabetic medication.

Authors:  Deborah Taira Juarez; Carolyn Ma; Audrey Kumasaka; Reid Shimada; James Davis
Journal:  Popul Health Manag       Date:  2014-08       Impact factor: 2.459

3.  Outcomes of a Problem-Solving Medication Management Intervention for Informal Caregivers.

Authors:  Judith A Erlen; Susan M Sereika; Ran Sun; Lisa K Tamres; Fengyan Tang; Jennifer H Lingler
Journal:  West J Nurs Res       Date:  2019-02-07       Impact factor: 1.967

4.  Determinants of adherence to diabetes medications: findings from a large pharmacy claims database.

Authors:  M Sue Kirkman; Megan T Rowan-Martin; Rebecca Levin; Vivian A Fonseca; Julie A Schmittdiel; William H Herman; Ronald E Aubert
Journal:  Diabetes Care       Date:  2015-01-08       Impact factor: 19.112

5.  Prescription Factors Associated with Medication Non-adherence in Japan Assessed from Leftover Drugs in the SETSUYAKU-BAG Campaign: Focus on Oral Antidiabetic Drugs.

Authors:  Kaori Koyanagi; Toshio Kubota; Daisuke Kobayashi; Taro Kihara; Takeo Yoshida; Takamasa Miisho; Tomoko Miura; Yoshiko Sakamoto; Junichi Takaki; Takashi Seo; Takao Shimazoe
Journal:  Front Pharmacol       Date:  2016-07-20       Impact factor: 5.810

6.  Validation of obesity-related diagnosis codes in claims data.

Authors:  Karine Suissa; Sebastian Schneeweiss; Kueiyu Joshua Lin; Gregory Brill; Seoyoung C Kim; Elisabetta Patorno
Journal:  Diabetes Obes Metab       Date:  2021-08-18       Impact factor: 6.577

7.  Treatment patterns and adherence to antihypertensive combination therapies in Japan using a claims database.

Authors:  Takayuki Ishida; Akinori Oh; Shinzo Hiroi; Yukio Shimasaki; Nobuhiro Nishigaki; Takuya Tsuchihashi
Journal:  Hypertens Res       Date:  2018-11-16       Impact factor: 3.872

8.  Prevalence and Correlates of Social Stigma Toward Diabetes: Results From a Nationwide- Survey in Singapore.

Authors:  Mythily Subramaniam; Edimansyah Abdin; S Bhuvaneswari; P V AshaRani; Fiona Devi; Kumarasan Roystonn; Peizhi Wang; Ellaisha Samari; Saleha Shafie; Janhavi Ajit Vaingankar; Rob M van Dam; Eng Sing Lee; Chee Fang Sum; Siow Ann Chong
Journal:  Front Psychol       Date:  2021-07-09

9.  Associations between adherence and outcomes among older, type 2 diabetes patients: evidence from a Medicare Supplemental database.

Authors:  Kristina Secnik Boye; Sarah E Curtis; Maureen J Lage; Luis-Emilio Garcia-Perez
Journal:  Patient Prefer Adherence       Date:  2016-08-16       Impact factor: 2.711

10.  Medication adherence in patients with diabetes mellitus: does physician drug dispensing enhance quality of care? Evidence from a large health claims database in Switzerland.

Authors:  Carola A Huber; Oliver Reich
Journal:  Patient Prefer Adherence       Date:  2016-09-15       Impact factor: 2.711

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