Literature DB >> 23715511

Convenient in situ generation of various dichlorinating agents from oxone and chloride: diastereoselective dichlorination of allylic and homoallylic alcohol derivatives.

Jingyun Ren1, Rongbiao Tong.   

Abstract

A safe and convenient protocol was developed for in situ generation of various dichlorinating agents (cf. Cl2, NCl3, Et4NCl3, ArICl2) from oxone and chloride. The synthetic utility of this protocol was demonstrated by diastereoselective dichlorination of a series of allylic and homoallylic alcohol derivatives with excellent yields and diastereoselectivity.

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Year:  2013        PMID： 23715511     DOI： 10.1039/c3ob40670a

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  3 in total

1.  Catalytic, stereospecific syn-dichlorination of alkenes.

Authors:  Alexander J Cresswell; Stanley T-C Eey; Scott E Denmark
Journal:  Nat Chem       Date:  2015-01-12       Impact factor: 24.427

Review 2.  Catalytic, Stereoselective Dihalogenation of Alkenes: Challenges and Opportunities.

Authors:  Alexander J Cresswell; Stanley T-C Eey; Scott E Denmark
Journal:  Angew Chem Int Ed Engl       Date:  2015-12-02       Impact factor: 15.336

3.  Green oxidation of indoles using halide catalysis.

Authors:  Jun Xu; Lixin Liang; Haohao Zheng; Yonggui Robin Chi; Rongbiao Tong
Journal:  Nat Commun       Date:  2019-10-18       Impact factor: 14.919
  3 in total

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