Literature DB >> 23715409

Vitamin B12: chemical modifications.

Keith o óProinsias1, Maciej Giedyk, Dorota Gryko.   

Abstract

Vitamin B12 plays a key role in many metabolic processes occurring in all mammals. Over the years its biological role has been extensively studied generating a lot of interest in the chemistry of this vital molecule. This established a variety of new methodologies for the synthesis and analysis of new cobalamin derivatives as well as creative purification techniques. This tutorial review summarizes all the advancements made in this area, providing a deeper insight into vitamin B12 chemistry.

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Year:  2013        PMID： 23715409     DOI： 10.1039/c3cs60062a

Source DB:  PubMed          Journal:  Chem Soc Rev        ISSN： 0306-0012            Impact factor:   54.564


  11 in total

1.  Unusual aerobic stabilization of Cob(I)alamin by a B12-trafficking protein allows chemoenzymatic synthesis of organocobalamins.

Authors:  Zhu Li; Nicholas A Lesniak; Ruma Banerjee
Journal:  J Am Chem Soc       Date:  2014-11-10       Impact factor: 15.419

2.  Solution Structure and Constrained Molecular Dynamics Study of Vitamin B12 Conjugates of the Anorectic Peptide PYY(3-36).

Authors:  Kelly E Henry; Deborah J Kerwood; Damian G Allis; Jayme L Workinger; Ron L Bonaccorso; George G Holz; Christian L Roth; Jon Zubieta; Robert P Doyle
Journal:  ChemMedChem       Date:  2016-03-30       Impact factor: 3.466

3.  Vitamin B12 as a carrier of peptide nucleic acid (PNA) into bacterial cells.

Authors:  Marcin Równicki; Monika Wojciechowska; Aleksandra J Wierzba; Jakub Czarnecki; Dariusz Bartosik; Dorota Gryko; Joanna Trylska
Journal:  Sci Rep       Date:  2017-08-09       Impact factor: 4.379

Review 4.  Learning from B12 enzymes: biomimetic and bioinspired catalysts for eco-friendly organic synthesis.

Authors:  Keishiro Tahara; Ling Pan; Toshikazu Ono; Yoshio Hisaeda
Journal:  Beilstein J Org Chem       Date:  2018-10-02       Impact factor: 2.883

5.  Vitamin B12 Deficiency Induces Imbalance in Melanocytes Homeostasis-A Cellular Basis of Hypocobalaminemia Pigmentary Manifestations.

Authors:  Zuzanna Rzepka; Michalina Respondek; Jakub Rok; Artur Beberok; Keith Ó Proinsias; Dorota Gryko; Dorota Wrześniok
Journal:  Int J Mol Sci       Date:  2018-09-19       Impact factor: 5.923

6.  Modulating the cobalt redox potential through imidazole hydrogen bonding interactions in a supramolecular biomimetic protein-cofactor model.

Authors:  Marjorie Sonnay; Thomas Fox; Olivier Blacque; Felix Zelder
Journal:  Chem Sci       Date:  2016-02-23       Impact factor: 9.825

7.  Systemically Administered Plant Recombinant Holo-Intrinsic Factor Targets the Liver and is not Affected by Endogenous B12 levels.

Authors:  Jayme L Workinger; Akhila N W Kuda-Wedagedara; Mara M Julin; Jordan M White; Ebba Nexo; Nerissa T Viola; Robert P Doyle
Journal:  Sci Rep       Date:  2019-08-22       Impact factor: 4.379

8.  Cobalamin Deficiency: Effect on Homeostasis of Cultured Human Astrocytes.

Authors:  Zuzanna Rzepka; Jakub Rok; Michalina Respondek; Justyna Pawlik; Artur Beberok; Dorota Gryko; Dorota Wrześniok
Journal:  Cells       Date:  2019-11-24       Impact factor: 6.600

9.  Resonance Raman Optical Activity Shows Unusual Structural Sensitivity for Systems in Resonance with Multiple Excited States: Vitamin B12 Case.

Authors:  Ewa Machalska; Grzegorz Zajac; Anna Gruca; Fabio Zobi; Malgorzata Baranska; Agnieszka Kaczor
Journal:  J Phys Chem Lett       Date:  2020-06-16       Impact factor: 6.475

Review 10.  Glucagon-like peptide-1 in diabetes care: Can glycaemic control be achieved without nausea and vomiting?

Authors:  Tito Borner; Ian C Tinsley; Robert P Doyle; Matthew R Hayes; Bart C De Jonghe
Journal:  Br J Pharmacol       Date:  2021-09-14       Impact factor: 8.739
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