OBJECTIVE: To identify and quantify various demographic, reproductive, socio-economic and dietary risk factors among women with breast cancer. STUDY DESIGN: Case control study. STUDY PERIOD: February 2004 to May 2005. STUDY SETTING: Departments of Surgery, Medicine and Radiotherapy of Jawaharlal Institute of Postgraduate Medical Sciences and Research (JIPMER), Pondicherry. MATERIALS AND METHODS: Cases were women with pathologically confirmed breast cancer. Controls were age-matched women from medicine and surgery wards without any current breast problem or previous breast cancer. A total of 152 cases and 152 controls were enrolled. They were interviewed for parity, breast feeding, past history of benign breast lesion, family history and dietary history with a pre-tested interview schedule after obtaining informed written consent. RESULTS: The significant risk factors were (odds ratios with 95% CI) previous history of biopsy for benign breast lesion 10.4 (1.3-86.3), nulliparity 2.4 (1.14-5.08), consumption of fats more than 30 g/day 2.4 (1.14-5.45) and consumption of oils containing more of saturated fat 2.0 (1.03-4.52). CONCLUSIONS: Nulliparity, past history of benign breast lesion, high fat diet and consumption of oils with more saturated fats were the risk factors.
OBJECTIVE: To identify and quantify various demographic, reproductive, socio-economic and dietary risk factors among women with breast cancer. STUDY DESIGN: Case control study. STUDY PERIOD: February 2004 to May 2005. STUDY SETTING: Departments of Surgery, Medicine and Radiotherapy of Jawaharlal Institute of Postgraduate Medical Sciences and Research (JIPMER), Pondicherry. MATERIALS AND METHODS: Cases were women with pathologically confirmed breast cancer. Controls were age-matched women from medicine and surgery wards without any current breast problem or previous breast cancer. A total of 152 cases and 152 controls were enrolled. They were interviewed for parity, breast feeding, past history of benign breast lesion, family history and dietary history with a pre-tested interview schedule after obtaining informed written consent. RESULTS: The significant risk factors were (odds ratios with 95% CI) previous history of biopsy for benign breast lesion 10.4 (1.3-86.3), nulliparity 2.4 (1.14-5.08), consumption of fats more than 30 g/day 2.4 (1.14-5.45) and consumption of oils containing more of saturated fat 2.0 (1.03-4.52). CONCLUSIONS: Nulliparity, past history of benign breast lesion, high fat diet and consumption of oils with more saturated fats were the risk factors.
Authors: G T Vondeling; G L Menezes; E P Dvortsin; F G A Jansman; I R Konings; M J Postma; M H Rozenbaum Journal: BMC Cancer Date: 2018-03-07 Impact factor: 4.430