Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Type I protein S deficiency and skin necrosis.

Literature DB >> 2371192

Type I protein S deficiency and skin necrosis.

A Craig¹, D A Taberner, A H Fisher, D N Foster, J Mitra.

Abstract

A kindred with Type I protein S deficiency is described in which the index case developed skin necrosis during induction of oral anticoagulant therapy for deep venous thrombosis. Two other family members with protein S deficiency have been detected, and demonstrate the clinical variability of this condition.

Entities: Disease

Mesh：

Substances：

Year: 1990 PMID： 2371192 PMCID： PMC2426848 DOI： 10.1136/pgmj.66.775.389

Source DB: PubMed Journal: Postgrad Med J ISSN： 0032-5473 Impact factor: 2.401

8 in total

1. Necrosis of skin induced by coumarin in a patient deficient in protein S.

Authors: V Grimaudo; F Gueissaz; J Hauert; A Sarraj; E K Kruithof; F Bachmann
Journal: BMJ Date: 1989-01-28

2. The frequency of type I heterozygous protein S and protein C deficiency in 141 unrelated young patients with venous thrombosis.

Authors: C L Gladson; I Scharrer; V Hach; K H Beck; J H Griffin
Journal: Thromb Haemost Date: 1988-02-25 Impact factor: 5.249

2 in total

Review 1. Coumarin-induced skin necrosis. Incidence, mechanisms, management and avoidance.

Authors: P C Comp
Journal: Drug Saf Date: 1993-02 Impact factor: 5.606

2. Cutaneous necrosis in pregnancy secondary to activated protein C resistance in hereditary angioedema.

Authors: W Perkins; I Downie; M Keefe; M Chisholm
Journal: J R Soc Med Date: 1995-04 Impact factor: 5.344

2 in total

Type I protein S deficiency and skin necrosis.

1. Necrosis of skin induced by coumarin in a patient deficient in protein S.

2. The frequency of type I heterozygous protein S and protein C deficiency in 141 unrelated young patients with venous thrombosis.

3. Protein C: a simplified semi-automated activity assay.

4. Recurrent venous thromboembolism in patients with a partial deficiency of protein S.

5. An abnormal plasma distribution of protein S occurs in functional protein S deficiency.

6. Decline of proteins C and S and factors II, VII, IX and X during the initiation of warfarin therapy.

Review 7. Formation of the fibrin clot: the balance of procoagulant and inhibitory factors.

8. Deficiency of protein C in congenital thrombotic disease.

Review 1. Coumarin-induced skin necrosis. Incidence, mechanisms, management and avoidance.

2. Cutaneous necrosis in pregnancy secondary to activated protein C resistance in hereditary angioedema.