Literature DB >> 23711739

Navigating personalized medicine dependent on modular flexibility.

Zhong Wang1, Yongyan Wang.   

Abstract

Deconstructing networks and rewiring alterable modules in a rational way is critical to optimize drug discovery and develop personalized medicine.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Mesh：

Year:  2013        PMID： 23711739     DOI： 10.1016/j.molmed.2013.05.003

Source DB:  PubMed          Journal:  Trends Mol Med        ISSN： 1471-4914            Impact factor:   11.951


  5 in total

1.  Fangjiomics: revealing adaptive omics pharmacological mechanisms of the myriad combination therapies to achieve personalized medicine.

Authors:  Dayue Darrel Duan; Zhong Wang; Bo-li Zhang; Yong-yan Wang
Journal:  Acta Pharmacol Sin       Date:  2015-06       Impact factor: 6.150

2.  Phenotype-dependent alteration of pathways and networks reveals a pure synergistic mechanism for compounds treating mouse cerebral ischemia.

Authors:  Peng-qian Wang; Bing Li; Jun Liu; Ying-ying Zhang; Ya-nan Yu; Xiao-xu Zhang; Ye Yuan; Zhi-li Guo; Hong-li Wu; Hai-xia Li; Hai-xia Dang; Shan-shan Guo; Zhong Wang
Journal:  Acta Pharmacol Sin       Date:  2015-05-11       Impact factor: 6.150

3.  System-wide assembly of pathways and modules hierarchically reveal metabolic mechanism of cerebral ischemia.

Authors:  Yan Zhu; Zhili Guo; Liangxiao Zhang; Yingying Zhang; Yinying Chen; Jingyi Nan; Buchang Zhao; Hongbin Xiao; Zhong Wang; Yongyan Wang
Journal:  Sci Rep       Date:  2015-12-01       Impact factor: 4.379

4.  IMCC: A Novel Quantitative Approach Revealing Variation of Global Modular Map and Local Inter-Module Coordination Among Differential Drug's Targeted Cerebral Ischemic Networks.

Authors:  Pengqian Wang; Yanan Yu; Jun Liu; Bing Li; Yingying Zhang; Dongfeng Li; Wenjuan Xu; Qiong Liu; Zhong Wang
Journal:  Front Pharmacol       Date:  2021-04-16       Impact factor: 5.810

5.  Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial.

Authors:  Jun Liu; Dan-Dan Li; Wei Dong; Yu-Qi Liu; Yang Wu; Da-Xuan Tang; Fu-Chun Zhang; Meng Qiu; Qi Hua; Jing-Yu He; Jun Li; Bai Du; Ting-Hai Du; Lin-Lin Niu; Xue-Jun Jiang; Bo Cui; Jiang-Bin Chen; Yang-Gan Wang; Hai-Rong Wang; Qin Yu; Jing He; Yi-Lin Mao; Xiao-Fang Bin; Yue Deng; Yu-Dan Tian; Qing-Hua Han; Da-Jin Liu; Li-Qin Duan; Ming-Jun Zhao; Cui-Ying Zhang; Hai-Ying Dai; Ze-Hua Li; Ying Xiao; You-Zhi Hu; Xiao-Yu Huang; Kun Xing; Xin Jiang; Chao-Feng Liu; Jing An; Feng-Chun Li; Tao Tao; Jin-Fa Jiang; Ying Yang; Yao-Rong Dong; Lei Zhang; Guang Fu; Ying Li; Shu-Wei Huang; Li-Ping Dou; Lan-Jun Sun; Ying-Qiang Zhao; Jie Li; Yun Xia; Jun Liu; Fan Liu; Wen-Jin He; Ying Li; Jian-Cong Tan; Yang Lin; Ya-Bin Zhou; Jian-Fei Yang; Guo-Qing Ma; Hui-Jun Chen; He-Ping Liu; Zong-Wu Liu; Jian-Xiong Liu; Xiao-Jia Luo; Xiao-Hong Bin; Ya-Nan Yu; Hai-Xia Dang; Bing Li; Fei Teng; Wang-Min Qiao; Xiao-Long Zhu; Bing-Wei Chen; Qi-Guang Chen; Chun-Ti Shen; Yong-Yan Wang; Yun-Dai Chen; Zhong Wang
Journal:  Signal Transduct Target Ther       Date:  2021-09-01
  5 in total

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