OBJECTIVE: To evaluate the correlation of chronic periodontitis in tropical area and IFN-γ, IL-10 and IL-17 levels. METHODS: One hundred and forty-eight patients and one hundred and thirty-two healthy control subjects were included in the study. Clinical parameters (PI, GI and PD) and GCF levels of IFN-γ, IL-10 and IL-17 were measured at baseline, week 8, week 16 and week 24 after mechanical removal of dental plaque. IFN-γ and IL-10 were determined with ELISA methods and IL-17 was determined with the cytometric bead array. RESULTS: Removal of dental plaque resulted in improvement in all clinical parameters. Meanwhile, GCF IL-17 declined to control levels, while GCF IFN-γ and IL-10 levels remained unchanged. CONCLUSIONS: The decline of GCF IL-17 levels in patients with resolution of periodontitis suggests that IL-17 is involved in the periodontal inflammatory process.
OBJECTIVE: To evaluate the correlation of chronic periodontitis in tropical area and IFN-γ, IL-10 and IL-17 levels. METHODS: One hundred and forty-eight patients and one hundred and thirty-two healthy control subjects were included in the study. Clinical parameters (PI, GI and PD) and GCF levels of IFN-γ, IL-10 and IL-17 were measured at baseline, week 8, week 16 and week 24 after mechanical removal of dental plaque. IFN-γ and IL-10 were determined with ELISA methods and IL-17 was determined with the cytometric bead array. RESULTS: Removal of dental plaque resulted in improvement in all clinical parameters. Meanwhile, GCFIL-17 declined to control levels, while GCF IFN-γ and IL-10 levels remained unchanged. CONCLUSIONS: The decline of GCFIL-17 levels in patients with resolution of periodontitis suggests that IL-17 is involved in the periodontal inflammatory process.
Authors: Kelly R V Villafuerte; Felipe T Dantas; Mario Taba; Michel Messora; Francisco J Candido Dos Reis; Hélio H A Carrara; Cristhiam de Jesus H Martinez; Thais Gozzo; Daniela Bazan Palioto Journal: Support Care Cancer Date: 2021-06-08 Impact factor: 3.603
Authors: Raed AlRowis; Hani S AlMoharib; Abdulrahman AlMubarak; Jagankumar Bhaskardoss; R S Preethanath; Sukumaran Anil Journal: J Int Oral Health Date: 2014-09
Authors: Luca Fiorillo; Gabriele Cervino; Alan Scott Herford; Floriana Lauritano; Cesare D'Amico; Roberto Lo Giudice; Luigi Laino; Giuseppe Troiano; Salvatore Crimi; Marco Cicciù Journal: Int J Mol Sci Date: 2018-06-29 Impact factor: 5.923