Literature DB >> 23710680

Synthesis of 6-(trifluoromethyl)phenanthridines via palladium-catalyzed tandem Suzuki/C-H arylation reactions.

Wen-Ying Wang1, Xia Feng, Bo-Lun Hu, Chen-Liang Deng, Xing-Guo Zhang.   

Abstract

A palladium-catalyzed tandem Suzuki/C-H arylation reaction of N-aryltrifluoroacetimidoyl chlorides with arylboronic acids has been developed. A variety of 6-(trifluoromethyl)phenanthridines were prepared in moderate to excellent yields from N-(2-bromophenyl)trifluoroacetimidoyl chlorides which can be conveniently prepared from 2-bromoaniline derivatives.

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Year:  2013        PMID: 23710680     DOI: 10.1021/jo4007255

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  2 in total

1.  Mechanism for phenanthridines synthesis by nitrogenation of 2-acetylbiphenyls in acidic solution: a DFT study.

Authors:  Lihui Guo; Fuqiang Zhang; Xiang Zhang
Journal:  J Mol Model       Date:  2016-10-28       Impact factor: 1.810

Review 2.  Come-back of phenanthridine and phenanthridinium derivatives in the 21st century.

Authors:  Lidija-Marija Tumir; Marijana Radić Stojković; Ivo Piantanida
Journal:  Beilstein J Org Chem       Date:  2014-12-10       Impact factor: 2.883

  2 in total

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