Literature DB >> 23709330

Fluorescein angiography-based diagnosis for retinopathy of prematurity: expert-non expert comparison.

Rosanna Guagliano1, Donatella Barillà, Chiara Bertone, Anna Maffia, Francesca Periti, Laura Spallone, Giovanni Anselmetti, Elisabetta Giacosa, Mauro Stronati, Carmine Tinelli, Paolo Emilio Bianchi.   

Abstract

PURPOSE: To evaluate accuracy and inter-rater reliability of RetCam fundus images and digital camera fluorangioscopic images in acute retinopathy of prematurity (ROP) by comparing diagnoses given by trainee ophthalmologists with those provided by expert ophthalmologists.
METHODS: This is a multicenter retrospective observational study of diagnostic data from 48 eyes of 24 premature infants with classical ROP, stage II, as evaluated by RetCam 3 and fluorescein angiography (FA). Average gestational age was 25.4 weeks, average weight 804.7 g. A staging grid (with ocular fundus divided into 3 concentric zones) and 24 15° sectors centered around the optic papilla were superimposed on 360° retina photomontages (Photoshop) made from RetCam and FA images. Non expert vs expert diagnosis agreement was measured for each sector by means of Cohen kappa (Fleiss, 1981).
RESULTS: A high degree of concordance was found. Inter-rater agreement between expert and non expert interpretations of retinal photomontages was greater for fluorangiographic images than for RetCam images, with κ = 0.61-1 for 120/152 (78.9%) sectors examined on the RetCam images and 
κ = 0.61-1 for 168/198 (84.8%) sectors examined on the FA images.
CONCLUSIONS: The FA images appear to be easier to interpret than RetCam images, both by expert and non expert ophthalmologists. The results confirm that FA is a good examination technique with a high degree of reliability, even where trainee practitioners are involved. This suggests that retinopathy management can be improved by entrusting diagnostic responsibilities to trainee ophthalmologists, in order to extend access to correct diagnosis, recognition of threshold lesions, and prompt treatment.

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Year:  2013        PMID: 23709330     DOI: 10.5301/ejo.5000319

Source DB:  PubMed          Journal:  Eur J Ophthalmol        ISSN: 1120-6721            Impact factor:   2.597


  4 in total

1.  Influence of Fluorescein Angiography on the Diagnosis and Management of Retinopathy of Prematurity.

Authors:  Michael A Klufas; Samir N Patel; Michael C Ryan; Mrinali Patel Gupta; Karyn E Jonas; Susan Ostmo; Maria Ana Martinez-Castellanos; Audina M Berrocal; Michael F Chiang; R V Paul Chan
Journal:  Ophthalmology       Date:  2015-05-28       Impact factor: 12.079

2.  Ultra-widefield fundus fluorescein angiography in pediatric retinal vascular diseases.

Authors:  Shreyas Temkar; Shorya V Azad; Rohan Chawla; Sourav Damodaran; Gaurav Garg; Harika Regani; Shaikh Nawazish; Nimmy Raj; Vatsalya Venkatraman
Journal:  Indian J Ophthalmol       Date:  2019-06       Impact factor: 1.848

3.  Optical coherence tomography angiography image quality assessment at varying retinal expertise levels.

Authors:  Anne K Woetzel; Jost L Lauermann; Kiana Kreitz; Maged Alnawaiseh; Christoph R Clemens; Nicole Eter; Florian Alten
Journal:  J Curr Ophthalmol       Date:  2018-12-27

4.  Fundus fluorescein angiography in retinopathy of prematurity.

Authors:  Amandeep Hans; Subina Narang; Meenakshi Sindhu; Suksham Jain; Deepak Chawla
Journal:  Eye (Lond)       Date:  2021-07-21       Impact factor: 4.456

  4 in total

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