Literature DB >> 23709145

Hypoparathyroidism presenting as cognitive dysfunction.

Gunjan Kumar1, Darshpreet Kaur, Puneet Aggarwal, Tilak Khurana.   

Abstract

Metabolic dysfunction in hypoparathyroidism is an important cause of intracranial calcifications, which cause cognitive impairment depending on the calcified areas leading to difficulties in executing activities of daily living. We report a case of a 25-year-old man who presented with gradually decreasing organisational skills, memory problems and difficulty in carrying out daily activities. CT imaging of the brain showed extensive calcification in the basal ganglia and cerebral white matter. Comprehensive health-related quality of life and cognitive assessment revealed significant affliction in his activities of daily living along with impairment in recall memory, executive functions and verbal fluency. Owing to late diagnosis, chronicity of cognitive problems could not prevent him from discontinuing his college education.

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Mesh:

Year:  2013        PMID: 23709145      PMCID: PMC3669969          DOI: 10.1136/bcr-2013-009220

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  7 in total

1.  Neurological picture. Extensive brain calcification in idiopathic hypoparathyroidism.

Authors:  M Mejdoubi; T Zegermann
Journal:  J Neurol Neurosurg Psychiatry       Date:  2006-12       Impact factor: 10.154

2.  The influence of age on trail making test performance.

Authors:  A D Davies
Journal:  J Clin Psychol       Date:  1968-01

3.  Cognitive impairment and intracranial calcification in chronic hypoparathyroidism.

Authors:  K V Kowdley; B M Coull; E S Orwoll
Journal:  Am J Med Sci       Date:  1999-05       Impact factor: 2.378

4.  Neuro-QOL: quality of life item banks for adults with neurological disorders: item development and calibrations based upon clinical and general population testing.

Authors:  Richard C Gershon; Jin Shei Lai; Rita Bode; Seung Choi; Claudia Moy; Tom Bleck; Deborah Miller; Amy Peterman; David Cella
Journal:  Qual Life Res       Date:  2011-08-27       Impact factor: 4.147

5.  The Rao's Brief Repeatable Battery and Stroop Test: normative values with age, education and gender corrections in an Italian population.

Authors:  M P Amato; E Portaccio; B Goretti; V Zipoli; L Ricchiuti; M F De Caro; F Patti; R Vecchio; S Sorbi; M Trojano
Journal:  Mult Scler       Date:  2006-12       Impact factor: 6.312

6.  The Stroop color-word test: influence of age, sex, and education; and normative data for a large sample across the adult age range.

Authors:  Wim Van der Elst; Martin P J Van Boxtel; Gerard J P Van Breukelen; Jelle Jolles
Journal:  Assessment       Date:  2006-03

7.  Intracranial bilateral symmetrical calcification on CT-scanning. A case report and a review of the literature.

Authors:  A Vakaet; R Rubens; J de Reuck; H vander Eecken
Journal:  Clin Neurol Neurosurg       Date:  1985       Impact factor: 1.876

  7 in total
  1 in total

Review 1.  The association between hypoparathyroidism and cognitive impairment: a systematic review.

Authors:  A Sardella; F Bellone; N Morabito; S Minisola; G Basile; F Corica; A Catalano
Journal:  J Endocrinol Invest       Date:  2020-09-14       Impact factor: 4.256

  1 in total

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