Literature DB >> 23709140

Cellular schwannoma masquerading as malignant peripheral nerve sheath tumour: a diagnostic dilemma.

Kiran Alam1, Anshu Jain, Aroonima Misra, A H Khan.   

Abstract

We present a case of a 15-year-old girl with a pulsatile, rapidly enlarging mass at the root of the nose suspected to be malignant. Excisional biopsy showed worrisome histological features; however, a final diagnosis of cellular schwannoma was reached excluding the possibility of malignant peripheral nerve sheath tumour by histological and immunohistochemical attributes. Cellular schwannoma, a pseudosarcomatous entity, is a rare benign neoplasm that may cause bone erosion and may be mistaken for a malignancy, clinically and histologically. Diagnosis of cellular schwannoma is essential to prevent mismanagement as it never metastasises and responds to local excision as opposed to aggressive treatment required by a malignant neoplasm.

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Year:  2013        PMID: 23709140      PMCID: PMC3669820          DOI: 10.1136/bcr-2012-008435

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  13 in total

1.  Cellular schwannoma: a rare presacral tumour.

Authors:  Erica J Patocskai; Maryam Tabatabaian; Meirion J Thomas
Journal:  Can J Surg       Date:  2002-04       Impact factor: 2.089

2.  Cellular schwannoma. A clinicopathologic study of 29 cases.

Authors:  P Lodding; L G Kindblom; L Angervall; G Stenman
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1990

3.  Giant intrasacral cellular schwannoma treated with high sacral amputation.

Authors:  M Takeyama; T Koshino; A Nakazawa; H Nitto; J Nakamura ; T Saito
Journal:  Spine (Phila Pa 1976)       Date:  2001-05-15       Impact factor: 3.468

4.  Cellular schwannoma: a distinct pseudosarcomatous entity.

Authors:  C D Fletcher; S E Davies; P H McKee
Journal:  Histopathology       Date:  1987-01       Impact factor: 5.087

5.  Cellular schwannoma: a benign neoplasm sometimes overdiagnosed as sarcoma.

Authors:  M Alberghini; L Zanella; P Bacchini; F Bertoni
Journal:  Skeletal Radiol       Date:  2001-06       Impact factor: 2.199

Review 6.  Cellular schwannoma.

Authors:  M Megahed; T Ruzicka
Journal:  Am J Dermatopathol       Date:  1994-08       Impact factor: 1.533

7.  Cellular schwannomas of the intracranial and intraspinal compartment: morphological and immunological characteristics compared with classical benign schwannomas.

Authors:  J P Deruaz; R C Janzer; J Costa
Journal:  J Neuropathol Exp Neurol       Date:  1993-03       Impact factor: 3.685

8.  Cellular schwannoma: a variety of schwannoma sometimes mistaken for a malignant tumor.

Authors:  J M Woodruff; T A Godwin; R A Erlandson; M Susin; N Martini
Journal:  Am J Surg Pathol       Date:  1981-12       Impact factor: 6.394

9.  Cellular schwannoma mimics a sarcoma: an example of a potential pitfall in aspiration cytodiagnosis.

Authors:  A C Henke; D R Salomao; J H Hughes
Journal:  Diagn Cytopathol       Date:  1999-05       Impact factor: 1.582

10.  Spinal malignant nerve-sheath tumor or cellular schwannoma? A striking difference in prognosis.

Authors:  M T Seppälä; M J Haltia
Journal:  J Neurosurg       Date:  1993-10       Impact factor: 5.115

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