| Literature DB >> 23707195 |
Yan-Li Zhang1, Wei-Sheng Feng, Xiao-Ke Zheng, Yan-Gang Cao, Yan-Yan Lv, Hui Chen, Hai-Xue Kuang.
Abstract
Three new ursane-type triterpenes, glutinosalactone A-C (1-3), were isolated from the 50% aqueous acetone extract of the leaves of Rehmannia glutinosa. Their structures were elucidated on the basis of spectral analysis (IR, NMR and MS spectroscopy). The cytotoxic effects of compounds 1-3 against three human cancer cell lines (MCF-7, MG63 and HepG2) were also evaluated. Compound 3 showed cytotoxic activities with IC50 values of 8.35-39.25 μM.Entities:
Keywords: Cytotoxic activity; Rehmannia glutinosa; Scrophulariaceae; Ursane-type triterpenes
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Year: 2013 PMID： 23707195 DOI： 10.1016/j.fitote.2013.05.013
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882