| Literature DB >> 23706732 |
Margaux Michel1, Patrick Cramer.
Abstract
Gene expression is largely regulated during the initiation of RNA polymerase II (PolII) transcription. In this issue, Kouzine et al. show that control of DNA melting is one of the critical rate-limiting steps for productive mRNA elongation. We discuss these findings in the context of other key energetic transitions.Mesh：
Year: 2013 PMID： 23706732 DOI： 10.1016/j.cell.2013.04.050
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582