Literature DB >> 23703785

Two-photon ratiometric fluorescent mapping of intracellular transport pathways of pH-responsive block copolymer micellar nanocarriers.

Tao Liu1, Jinming Hu, Zhenyu Jin, Fan Jin, Shiyong Liu.   

Abstract

Ultrasensitive ratiometric fluorescent pH probes based on dual dye-labeled pH-responsive diblock copolymer micellar scaffold are constructed. The pH-sensitive emitting nature of BTPE dyes and emission turn-on of CMA moieties triggered by pH-actuated micelle-to-unimer of diblock scaffold synergistically contribute to the observed ≈250-fold changes of BTPE/CMA emission intensity ratios in the whole pH range. Two-photon ratiometric fluorescent pH mapping of intracellular gradients subjected by pH-responsive micellar nanoparticles in their endocytic pathway has been thus achieved.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  diblock copolymer micelles; endocytic pathway; intracellular imaging; pH gradients; ratiometric quantification

Mesh：

Substances：

Year:  2013        PMID： 23703785     DOI： 10.1002/adhm.201200436

Source DB:  PubMed          Journal:  Adv Healthc Mater        ISSN： 2192-2640            Impact factor:   9.933


  6 in total

1.  Optical Sensing and Imaging of pH Values: Spectroscopies, Materials, and Applications.

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2.  Self-folded redox/acid dual-responsive nanocarriers for anticancer drug delivery.

Authors:  Yue Lu; Ran Mo; Wanyi Tai; Wujin Sun; Dennis B Pacardo; Chenggen Qian; Qundong Shen; Frances S Ligler; Zhen Gu
Journal:  Chem Commun (Camb)       Date:  2014-12-11       Impact factor: 6.222

Review 3.  Ratiometric optical nanoprobes enable accurate molecular detection and imaging.

Authors:  Xiaolin Huang; Jibin Song; Bryant C Yung; Xiaohua Huang; Yonghua Xiong; Xiaoyuan Chen
Journal:  Chem Soc Rev       Date:  2018-04-23       Impact factor: 54.564

4.  Ratiometric intracellular pH sensors based on nitrogen-doped graphene oxide quantum dots.

Authors:  Xiang Zhang; Yu Gu; Yun Zhang; Guo-Yin Yu; Zhi-Peng Liao; Hui-Fang Wu; Chuan-Guo Shi
Journal:  Heliyon       Date:  2022-05-13

5.  Fluorescent Block Copolymer Micelles That Can Self-Report on Their Assembly and Small Molecule Encapsulation.

Authors:  Mathew P Robin; Shani A M Osborne; Zoe Pikramenou; Jeffery E Raymond; Rachel K O'Reilly
Journal:  Macromolecules       Date:  2016-01-06       Impact factor: 5.985

Review 6.  Supramolecular Chirality in Azobenzene-Containing Polymer System: Traditional Postpolymerization Self-Assembly Versus In Situ Supramolecular Self-Assembly Strategy.

Authors:  Xiaoxiao Cheng; Tengfei Miao; Yilin Qian; Zhengbiao Zhang; Wei Zhang; Xiulin Zhu
Journal:  Int J Mol Sci       Date:  2020-08-27       Impact factor: 5.923
  6 in total

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