| Literature DB >> 23702540 |
Teresa Piovesan1, Steven M Kelk.
Abstract
Here, we present a new fixed parameter tractable algorithm to compute the hybridization number r of two rooted, not necessarily binary phylogenetic trees on taxon set Χ in time (6(r)r!) · poly(n), where n = |Χ|. The novelty of this approach is its use of terminals, which are maximal elements of a natural partial order on Χ, and several insights from the softwired clusters literature. This yields a surprisingly simple and practical bounded-search algorithm and offers an alternative perspective on the underlying combinatorial structure of the hybridization number problem.Mesh:
Year: 2013 PMID: 23702540 DOI: 10.1109/TCBB.2012.134
Source DB: PubMed Journal: IEEE/ACM Trans Comput Biol Bioinform ISSN: 1545-5963 Impact factor: 3.710