| Literature DB >> 23698727 |
Hale Unal Aksu1, Ender Oner2, Omer Celik2, Nilgun Isiksacan3, Huseyin Aksu2, Sami Uzun4, Derya Yavuz5, Savas Ozturk4, Mehmet Gul2, Nevzat Uslu2.
Abstract
The aim of this study was to evaluate the prevalence of aspirin resistance (AR) in patients undergoing hemodialysis (HD) and to assess the effect of HD on the results of the Multiplate test. A total of 54 patients undergoing HD were included in this study. Blood samples were taken just before and after the HD session. To determine AR, we used Multiplate test. Platelet aggregation values of the study population were 363.01 ± 225.69 aggregation unit (AU) × minutes before and 375.33 ± 254.05 AU × minutes after the HD (P = .597). There was strong correlation between the values before and after HD (R = .755, P < .0001). The AR status was changed in 9 (16.6%) patients after HD. Agreement of AR status before and after HD was substantial (κ coefficient = .667, P < .0001). The prevalence of AR in patients undergoing HD seems higher than in most of the studied populations, and this study has shown that the AR statuses of a significant number of patients undergoing HD change after an HD session.Entities:
Keywords: Multiplate test; aspirin resistance; hemodialysis
Mesh：
Substances：
Year: 2013 PMID： 23698727 DOI： 10.1177/1076029613489597
Source DB: PubMed Journal: Clin Appl Thromb Hemost ISSN： 1076-0296 Impact factor: 2.389