Literature DB >> 2369845

The receptors for prolactin and growth hormone are localized in the same region of human chromosome 5.

K C Arden1, J M Boutin, J Djiane, P A Kelly, W K Cavenee.   

Abstract

Prolactin receptor (PRLR) and growth hormone receptor (GHR) are encoded by members of a gene family containing regions of identical sequences. To determine their chromosomal locations, cDNA probes for these genes were used. Analysis of hybridization to several somatic cell hybrids, together with hybridization in situ to metaphase chromosomes, resulted in the assignment of the loci for both receptors to human chromosome 5 in the region p13----p14. Thus, these proteins may be encoded by a cluster of related genes that evolved from a common ancestral gene, in a manner consonant with that of their ligands.

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Year:  1990        PMID： 2369845     DOI： 10.1159/000132919

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN： 0301-0171


  9 in total

Review 1.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

2.  The interleukin-7 receptor gene is at 5p13.

Authors:  M Lynch; E Baker; L S Park; G R Sutherland; R G Goodwin
Journal:  Hum Genet       Date:  1992-07       Impact factor: 4.132

Review 3.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

4.  Localization of a Moloney murine leukemia virus integration site gene, Mlvi2, on rat chromosome 2.

Authors:  T Kunieda; E Kobayashi; M Tachibana; H Ikadai
Journal:  Mamm Genome       Date:  1996-12       Impact factor: 2.957

Review 5.  New insights in prolactin: pathological implications.

Authors:  Valérie Bernard; Jacques Young; Philippe Chanson; Nadine Binart
Journal:  Nat Rev Endocrinol       Date:  2015-03-17       Impact factor: 43.330

Review 6.  Prolactin regulation of the prostate gland: a female player in a male game.

Authors:  Vincent Goffin; David T Hoang; Roman L Bogorad; Marja T Nevalainen
Journal:  Nat Rev Urol       Date:  2011-10-04       Impact factor: 14.432

7.  Activation of the prolactin receptor gene by promoter insertion in a Moloney murine leukemia virus-induced rat thymoma.

Authors:  C S Barker; S E Bear; T Keler; N G Copeland; D J Gilbert; N A Jenkins; R S Yeung; P N Tsichlis
Journal:  J Virol       Date:  1992-11       Impact factor: 5.103

8.  Different chromosomal localization of two adenylyl cyclase genes expressed in human brain.

Authors:  D Stengel; J Parma; M H Gannagé; N Roeckel; M G Mattei; R Barouki; J Hanoune
Journal:  Hum Genet       Date:  1992 Sep-Oct       Impact factor: 4.132

9.  A comprehensive analysis of common genetic variation in prolactin (PRL) and PRL receptor (PRLR) genes in relation to plasma prolactin levels and breast cancer risk: the multiethnic cohort.

Authors:  Sulggi A Lee; Christopher A Haiman; Noel P Burtt; Loreall C Pooler; Iona Cheng; Laurence N Kolonel; Malcolm C Pike; David Altshuler; Joel N Hirschhorn; Brian E Henderson; Daniel O Stram
Journal:  BMC Med Genet       Date:  2007-12-01       Impact factor: 2.103
  9 in total

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