Literature DB >> 23698291

Reverse genetics identifies the product of open reading frame 4 as an essential particle assembly factor of Nyamanini virus.

Marieke Herrel1, Lars Haag, Josefina Nilsson, Peter Staeheli, Urs Schneider.   

Abstract

We established a reverse genetics system for Nyamanini virus (NYMV) and recovered green fluorescent protein (GFP)-expressing virus from full-length cDNA. Using this technology, we assessed the functions of two poorly characterized viral genes. NYMV lacking open reading frame 2 (ORF2) could not be rescued, whereas virus lacking ORF4 was replication competent. ORF4-deficient NYMV readily established a persisting noncytolytic infection but failed to produce infectious viral particles, supporting the view that ORF4 represents an essential factor for NYMV particle assembly.

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Year:  2013        PMID： 23698291      PMCID： PMC3700212          DOI： 10.1128/JVI.00163-13

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  14 in total

1.  A new Sendai virus vector deficient in the matrix gene does not form virus particles and shows extensive cell-to-cell spreading.

Authors:  Makoto Inoue; Yumiko Tokusumi; Hiroshi Ban; Takumi Kanaya; Masayuki Shirakura; Tsuyoshi Tokusumi; Takahiro Hirata; Yoshiyuki Nagai; Akihiro Iida; Mamoru Hasegawa
Journal:  J Virol       Date:  2003-06       Impact factor: 5.103

2.  Biochemical and functional characterization of the Ebola virus VP24 protein: implications for a role in virus assembly and budding.

Authors:  Ziying Han; Hani Boshra; J Oriol Sunyer; Susan H Zwiers; Jason Paragas; Ronald N Harty
Journal:  J Virol       Date:  2003-02       Impact factor: 5.103

3.  The X protein of Borna disease virus regulates viral polymerase activity through interaction with the P protein.

Authors:  Marion Poenisch; Gunhild Unterstab; Thorsten Wolff; Peter Staeheli; Urs Schneider
Journal:  J Gen Virol       Date:  2004-07       Impact factor: 3.891

4.  VP24 of Marburg virus influences formation of infectious particles.

Authors:  Sandra Bamberg; Larissa Kolesnikova; Peggy Möller; Hans-Dieter Klenk; Stephan Becker
Journal:  J Virol       Date:  2005-11       Impact factor: 5.103

Review 5.  Virus maturation by budding.

Authors:  H Garoff; R Hewson; D J Opstelten
Journal:  Microbiol Mol Biol Rev       Date:  1998-12       Impact factor: 11.056

6.  RNA polymerase II-controlled expression of antigenomic RNA enhances the rescue efficacies of two different members of the Mononegavirales independently of the site of viral genome replication.

Authors:  Arnold Martin; Peter Staeheli; Urs Schneider
Journal:  J Virol       Date:  2006-06       Impact factor: 5.103

7.  Identification of the Borna disease virus (BDV) proteins required for the formation of BDV-like particles.

Authors:  Mar Perez; Juan Carlos de la Torre
Journal:  J Gen Virol       Date:  2005-07       Impact factor: 3.891

Review 8.  Negative-strand virus M and retrovirus MA proteins: all in a family?

Authors:  J Lenard
Journal:  Virology       Date:  1996-02-15       Impact factor: 3.616

9.  Nyamiviridae: proposal for a new family in the order Mononegavirales.

Authors:  Jens H Kuhn; Sadia Bekal; Yíngyún Caì; Anna N Clawson; Leslie L Domier; Marieke Herrel; Peter B Jahrling; Hideki Kondo; Kris N Lambert; Kathie A Mihindukulasuriya; Norbert Nowotny; Sheli R Radoshitzky; Urs Schneider; Peter Staeheli; Nobuhiro Suzuki; Robert B Tesh; David Wang; Lin-Fa Wang; Ralf G Dietzgen
Journal:  Arch Virol       Date:  2013-05-01       Impact factor: 2.574

10.  A matrix-less measles virus is infectious and elicits extensive cell fusion: consequences for propagation in the brain.

Authors:  T Cathomen; B Mrkic; D Spehner; R Drillien; R Naef; J Pavlovic; A Aguzzi; M A Billeter; R Cattaneo
Journal:  EMBO J       Date:  1998-07-15       Impact factor: 11.598
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  2 in total

1.  The Integrity of the YxxL Motif of Ebola Virus VP24 Is Important for the Transport of Nucleocapsid-Like Structures and for the Regulation of Viral RNA Synthesis.

Authors:  Yuki Takamatsu; Larissa Kolesnikova; Martin Schauflinger; Takeshi Noda; Stephan Becker
Journal:  J Virol       Date:  2020-04-16       Impact factor: 5.103

Review 2.  Reverse genetics of Mononegavirales: How they work, new vaccines, and new cancer therapeutics.

Authors:  Christian K Pfaller; Roberto Cattaneo; Matthias J Schnell
Journal:  Virology       Date:  2015-02-18       Impact factor: 3.616
  2 in total

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