| Literature DB >> 23696693 |
Chi Zhang1, Yong Zhou, Chiye Li, Lihong V Wang.
Abstract
We propose to enhance the axial resolution of photoacoustic microscopy (PAM) by reducing the speed of sound within the imaging region of interest. With silicone oil immersion, we have achieved a finest axial resolution of 5.8 μm for PAM, as validated by phantom experiments. The axial resolution was also enhanced in vivo when mouse ears injected with silicone oil were imaged. When tissue-compatible low-speed liquid becomes available, this approach may find broad applications in PAM as well as in other imaging modalities, such as photoacoustic computed tomography and ultrasound imaging.Entities:
Year: 2013 PMID: 23696693 PMCID: PMC3651204 DOI: 10.1063/1.4803444
Source DB: PubMed Journal: Appl Phys Lett ISSN: 0003-6951 Impact factor: 3.791