Literature DB >> 2369436

The use of sedative-hypnotic drugs in a university teaching hospital.

R O'Reilly1, C Rusnak.   

Abstract

We reviewed the charts of 476 patients admitted to a university teaching hospital to determine whether sedative-hypnotic drugs (SHDs) were being used excessively and to examine the use of SHDs as hypnotics. The frequency of medical and surgical indications for barbiturates and benzodiazepines or other minor tranquillizers as well as the use of such drugs were compared among different groups of patients and specialty wards. Of the patients 29% had a regular order and 40% had a PRN order; only 77% of the PRN orders were administered. A total of 215 patients (45%) received an SHD during their hospital stay, and 160 (34%) received the drug as a hypnotic. Medical indications accounted for 49% of the regular orders but only 2% of the PRN orders; moreover, 89% of all the PRN orders were for insomnia. On average, patients receiving SHDs as hypnotics were older (p less than 0.05) and stayed longer in hospital (p less than 0.01) than those who did not; however, no patient on the geriatric or pediatric ward received an SHD as a hypnotic during the hospital stay. The differences in use between patient groups may have been influenced by orientation of ward staff. Physicians should review their rationale for prescribing hypnotics and avoid routine orders on admission.

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Year:  1990        PMID: 2369436      PMCID: PMC1451884     

Source DB:  PubMed          Journal:  CMAJ        ISSN: 0820-3946            Impact factor:   8.262


  21 in total

1.  Sleep insurance: a valid use of hypnotics?

Authors:  D Morrison; D G Mayfield
Journal:  N C Med J       Date:  1972-10

2.  Dependence on hypnotic drugs in general practice.

Authors:  J Johnson; A D Clift
Journal:  Br Med J       Date:  1968-12-07

3.  Clinical effects of hypnotics. II. An epidemiologic study.

Authors:  S Shapiro; D Slone; G P Lewis; H Jick
Journal:  JAMA       Date:  1969-09-29       Impact factor: 56.272

4.  Evaluating the effectiveness of a process medical audit in a teaching general hospital.

Authors:  R W Brooks-Hill; R A Buckingham
Journal:  CMAJ       Date:  1986-02-15       Impact factor: 8.262

5.  Anti-anxiety agents: duration of use and characteristics of users in the U.S.A.

Authors:  G D Mellinger; M B Balter; E H Uhlenhuth
Journal:  Curr Med Res Opin       Date:  1984       Impact factor: 2.580

6.  Reducing night sedation in psychogeriatric wards.

Authors:  A F Mulligan; C P O'Grady
Journal:  Nurs Times       Date:  1971-09-02

7.  Requests for hypnotic drugs and placebo response in elderly hospital in-patients.

Authors:  A J Bayer; M S Pathy
Journal:  Postgrad Med J       Date:  1985-04       Impact factor: 2.401

8.  Rationale for the use of hypnotic agents in a general hospital.

Authors:  S W Perry; A Wu
Journal:  Ann Intern Med       Date:  1984-03       Impact factor: 25.391

9.  A cross-national comparison of anti-anxiety/sedative drug use.

Authors:  M B Balter; D I Manheimer; G D Mellinger; E H Uhlenhuth
Journal:  Curr Med Res Opin       Date:  1984       Impact factor: 2.580

10.  Self-reported use of psychotropic drugs and alcohol abuse in South-Verona.

Authors:  O Siciliani; C Bellantuono; P Williams; M Tansella
Journal:  Psychol Med       Date:  1985-11       Impact factor: 7.723

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  7 in total

1.  The use of hypnosedative drugs in a university hospital: has anything changed in 10 years?

Authors:  Annemie Somers; Hugo Robays; Kurt Audenaert; Georges Van Maele; Marc Bogaert; Mirko Petrovic
Journal:  Eur J Clin Pharmacol       Date:  2011-01-29       Impact factor: 2.953

2.  The use of sedative-hypnotic drugs in a university teaching hospital.

Authors:  J Lexchin
Journal:  CMAJ       Date:  1990-05-15       Impact factor: 8.262

Review 3.  The socioeconomic impact of insomnia. An overview.

Authors:  L A Chilcott; C M Shapiro
Journal:  Pharmacoeconomics       Date:  1996       Impact factor: 4.981

4.  Moderating Benzodiazepine Use in the Elderly: Curbing physicians' prescribing practices.

Authors:  P G Huston
Journal:  Can Fam Physician       Date:  1992-10       Impact factor: 3.275

5.  Benzodiazepine prescription and length of hospital stay at a Japanese university hospital.

Authors:  Mutsuhiro Nakao; Mikiya Sato; Kyoko Nomura; Eiji Yano
Journal:  Biopsychosoc Med       Date:  2009-10-09

6.  Improving sedative-hypnotic prescribing in older hospitalized patients: provider-perceived benefits and barriers of a computer-based reminder.

Authors:  Joseph V Agostini; John Concato; Sharon K Inouye
Journal:  J Gen Intern Med       Date:  2008-01       Impact factor: 5.128

Review 7.  Sleep disturbance in older ICU patients.

Authors:  Roxanne Sterniczuk; Benjamin Rusak; Kenneth Rockwood
Journal:  Clin Interv Aging       Date:  2014-06-23       Impact factor: 4.458

  7 in total

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