Literature DB >> 23692378

Advancing translational research through the NHLBI Gene Therapy Resource Program (GTRP).

Cheryl L McDonald1, Janet Benson, Kenneth Cornetta, Margaret Diggins, Julie C Johnston, Susan Sepelak, Gensheng Wang, James M Wilson, J Fraser Wright, Sonia I Skarlatos.   

Abstract

Abstract Translational research is a lengthy, complex, and necessary endeavor in order to bring basic science discoveries to clinical fruition. The NIH offers several programs to support translational research including an important resource established specifically for gene therapy researchers-the National Heart, Lung, and Blood Institute (NHLBI) Gene Therapy Resource Program (GTRP). This paper reviews the core components of the GTRP and describes how the GTRP provides researchers with resources that are critical to advancing investigational gene therapy products into clinical testing.

Mesh:

Year:  2013        PMID: 23692378      PMCID: PMC4003470          DOI: 10.1089/humc.2013.036

Source DB:  PubMed          Journal:  Hum Gene Ther Clin Dev        ISSN: 2324-8637            Impact factor:   5.032


  7 in total

1.  Medicine. The NIH Roadmap.

Authors:  Elias Zerhouni
Journal:  Science       Date:  2003-10-03       Impact factor: 47.728

2.  US biomedical research: basic, translational, and clinical sciences.

Authors:  Elias A Zerhouni
Journal:  JAMA       Date:  2005-09-21       Impact factor: 56.272

3.  Critical resources for gene therapy in Heart, Lung, and Blood Diseases Working Group.

Authors:  Savio L C Woo; Sonia I Skarlatos; Mary M Joyce; Thomas L Croxton; Pankaj Qasba
Journal:  Mol Ther       Date:  2006-04       Impact factor: 11.454

4.  Clinical and translational science awards: a framework for a national research agenda.

Authors:  Elias A Zerhouni; Barbara Alving
Journal:  Transl Res       Date:  2006-07       Impact factor: 7.012

5.  Research agenda. Opportunities for research and NIH.

Authors:  Francis S Collins
Journal:  Science       Date:  2010-01-01       Impact factor: 47.728

6.  Reengineering translational science: the time is right.

Authors:  Francis S Collins
Journal:  Sci Transl Med       Date:  2011-07-06       Impact factor: 17.956

7.  Summary statement of the Asilomar conference on recombinant DNA molecules.

Authors:  P Berg; D Baltimore; S Brenner; R O Roblin; M F Singer
Journal:  Proc Natl Acad Sci U S A       Date:  1975-06       Impact factor: 11.205

  7 in total
  3 in total

Review 1.  Dr. Sonia Skarlatos and the National Heart, Lung, and Blood institute translational research and resource programs.

Authors:  Cheryl L McDonald
Journal:  Hum Gene Ther       Date:  2013-11       Impact factor: 5.695

2.  The Gene Therapy Resource Program: A Decade of Dedication to Translational Research by the National Heart, Lung, and Blood Institute.

Authors:  Terence R Flotte; Eric Daniels; Janet Benson; Jeneé M Bevett-Rose; Kenneth Cornetta; Margaret Diggins; Julie Johnston; Susan Sepelak; Johannes C M van der Loo; James M Wilson; Cheryl L McDonald
Journal:  Hum Gene Ther Clin Dev       Date:  2017-11-27       Impact factor: 5.032

Review 3.  Adeno-associated virus-mediated gene therapy for metabolic myopathy.

Authors:  Cathryn S Mah; Meghan S Soustek; A Gary Todd; Angela McCall; Barbara K Smith; Manuela Corti; Darin J Falk; Barry J Byrne
Journal:  Hum Gene Ther       Date:  2013-11       Impact factor: 5.695

  3 in total

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