Literature DB >> 23690516

Obesity in men with childhood ADHD: a 33-year controlled, prospective, follow-up study.

Samuele Cortese1, Maria A Ramos Olazagasti, Rachel G Klein, F Xavier Castellanos, Erika Proal, Salvatore Mannuzza.   

Abstract

OBJECTIVE: To compare BMI and obesity rates in fully grown men with and without childhood attention-deficit/hyperactivity disorder (ADHD). We predicted higher BMI and obesity rates in: (1) men with, versus men without, childhood ADHD; (2) men with persistent, versus men with remitted, ADHD; and (3) men with persistent or remitted ADHD versus those without childhood ADHD.
METHODS: Men with childhood ADHD were from a cohort of 207 white boys (referred at a mean age of 8.3 years), interviewed blindly at mean ages 18 (FU18), 25 (FU25), and 41 years (FU41). At FU18, 178 boys without ADHD were recruited. At FU41, 111 men with childhood ADHD and 111 men without childhood ADHD self-reported their weight and height.
RESULTS: Men with childhood ADHD had significantly higher BMI (30.1 ± 6.3 vs 27.6 ± 3.9; P = .001) and obesity rates (41.4% vs 21.6%; P = .001) than men without childhood ADHD. Group differences remained significant after adjustment for socioeconomic status and lifetime mental disorders. Men with persistent (n = 24) and remitted (n = 87) ADHD did not differ significantly in BMI or obesity rates. Even after adjustment, men with remitted (but not persistent) ADHD had significantly higher BMI (B: 2.86 [95% CI: 1.22 to 4.50]) and obesity rates (odds ratio: 2.99 [95% CI: 1.55 to 5.77]) than those without childhood ADHD.
CONCLUSIONS: Children with ADHD are at increased risk of obesity as adults. Findings of elevated BMI and obesity rates in men with remitted ADHD require replication.

Entities:  

Keywords:  ADHD; BMI; adults; longitudinal follow-up; obesity; weight

Mesh:

Year:  2013        PMID: 23690516      PMCID: PMC4074659          DOI: 10.1542/peds.2012-0540

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  35 in total

1.  Impact of the impairment criterion in the diagnosis of adult ADHD: 33-year follow-up study of boys with ADHD.

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2.  A teacher rating scale for use in drug studies with children.

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Journal:  Am J Psychiatry       Date:  1969-12       Impact factor: 18.112

3.  Examining the relationship between attention-deficit/hyperactivity disorder and overweight in children and adolescents.

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4.  Hyperactive boys almost grown up. III. Methylphenidate effects on ultimate height.

Authors:  R G Klein; S Mannuzza
Journal:  Arch Gen Psychiatry       Date:  1988-12

5.  Successful methylphenidate treatment of early onset extreme obesity in a child with a melanocortin-4 receptor gene mutation and attention deficit/hyperactivity disorder.

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6.  A naturalistic 10-year prospective study of height and weight in children with attention-deficit hyperactivity disorder grown up: sex and treatment effects.

Authors:  Joseph Biederman; Thomas J Spencer; Michael C Monuteaux; Stephen V Faraone
Journal:  J Pediatr       Date:  2010-10       Impact factor: 4.406

7.  Lifetime criminality among boys with attention deficit hyperactivity disorder: a prospective follow-up study into adulthood using official arrest records.

Authors:  Salvatore Mannuzza; Rachel G Klein; John L Moulton
Journal:  Psychiatry Res       Date:  2008-08-15       Impact factor: 3.222

8.  Hyperactive boys almost grown up. V. Replication of psychiatric status.

Authors:  S Mannuzza; R G Klein; N Bonagura; P Malloy; T L Giampino; K A Addalli
Journal:  Arch Gen Psychiatry       Date:  1991-01

9.  Attention deficit hyperactivity disorder in obese melanocortin-4-receptor (MC4R) deficient subjects: a newly described expression of MC4R deficiency.

Authors:  Anat Agranat-Meged; Yoad Ghanadri; Iris Eisenberg; Ziva Ben Neriah; Eva Kieselstein-Gross; Stella Mitrani-Rosenbaum
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10.  Hyperactive boys almost grown up. I. Psychiatric status.

Authors:  R Gittelman; S Mannuzza; R Shenker; N Bonagura
Journal:  Arch Gen Psychiatry       Date:  1985-10
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  36 in total

1.  Sex and racial/ethnic differences in the association between childhood attention-deficit/hyperactivity disorder symptom subtypes and body mass index in the transition from adolescence to adulthood in the United States.

Authors:  Y Inoue; A G Howard; A Stickley; A Yazawa; P Gordon-Larsen
Journal:  Pediatr Obes       Date:  2019-01-10       Impact factor: 4.000

2.  Attention deficit disorder, stimulant use, and childhood body mass index trajectory.

Authors:  Brian S Schwartz; Lisa Bailey-Davis; Karen Bandeen-Roche; Jonathan Pollak; Annemarie G Hirsch; Claudia Nau; Ann Y Liu; Thomas A Glass
Journal:  Pediatrics       Date:  2014-03-17       Impact factor: 7.124

3.  A Randomized Controlled Trial of Interventions for Growth Suppression in Children With Attention-Deficit/Hyperactivity Disorder Treated With Central Nervous System Stimulants.

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Review 4.  Attention-deficit/hyperactivity disorder (ADHD) and being overweight/obesity: New data and meta-analysis.

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Journal:  Clin Psychol Rev       Date:  2015-12-02

5.  Inhibitory control in otherwise healthy overweight 10-year-old children.

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6.  Childhood Attention-Deficit/Hyperactivity Disorder, Sex, and Obesity: A Longitudinal Population-Based Study.

Authors:  Roxana L Aguirre Castaneda; Seema Kumar; Robert G Voigt; Cynthia L Leibson; William J Barbaresi; Amy L Weaver; Jill M Killian; Slavica K Katusic
Journal:  Mayo Clin Proc       Date:  2016-02-04       Impact factor: 7.616

Review 7.  Overlapping neurobehavioral circuits in ADHD, obesity, and binge eating: evidence from neuroimaging research.

Authors:  Karen E Seymour; Shauna P Reinblatt; Leora Benson; Susan Carnell
Journal:  CNS Spectr       Date:  2015-08       Impact factor: 3.790

8.  Latent profile analysis of neuropsychological measures to determine preschoolers' risk for ADHD.

Authors:  Khushmand Rajendran; Sarah O'Neill; David J Marks; Jeffrey M Halperin
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9.  Are Eating Disorders Related to Attention Deficit/Hyperactivity Disorder?

Authors:  Shauna P Reinblatt
Journal:  Curr Treat Options Psychiatry       Date:  2015-10-09

10.  The role of genetic and environmental influences on the association between childhood ADHD symptoms and BMI.

Authors:  Elizabeth K Do; Brett C Haberstick; Redford B Williams; Jeffrey M Lessem; Andrew Smolen; Ilene C Siegler; Bernard F Fuemmeler
Journal:  Int J Obes (Lond)       Date:  2018-10-22       Impact factor: 5.095

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