OBJECTIVES: To investigate cardiorespiratory and inflammatory responses in male workers following exposure to welding fumes and airborne particles in actual workplace conditions. MATERIALS AND METHODS: We measured blood leukocytes and their differential counts, platelet count, hemoglobin, sensitive C-reactive protein, fibrinogen, E-selectin, IL-(interleukin)1β, IL-6, IL-8, tumor necrosis factor alpha (TNF-α) and endothelin-1 in blood samples of twenty workers before and after their working day. We also studied peak expiratory flow (PEF), forced expiratory volume in one second (FEV1), and exhaled nitric oxide (NO). We assessed heart rate variability (HRV) by obtaining 24-hour ambulatory electrocardiograms. RESULTS: The total blood leukocytes and neutrophils increased after the work shift, whereas IL-1β and E-selectin decreased significantly. There were no statistically significant changes in exhaled NO, FEV1, PEF or HRV. CONCLUSION: Occupational exposure to welding fumes and particles caused a slight, acute inflammatory effect estimated based on the increased values of leukocytes and neutrophils in blood and a decrease in the interleukin 1β and E-selectin values, but no changes in the pulmonary function (exhaled NO, FEV1, PEF) or HRV during the working day were observed.
OBJECTIVES: To investigate cardiorespiratory and inflammatory responses in male workers following exposure to welding fumes and airborne particles in actual workplace conditions. MATERIALS AND METHODS: We measured blood leukocytes and their differential counts, platelet count, hemoglobin, sensitive C-reactive protein, fibrinogen, E-selectin, IL-(interleukin)1β, IL-6, IL-8, tumor necrosis factor alpha (TNF-α) and endothelin-1 in blood samples of twenty workers before and after their working day. We also studied peak expiratory flow (PEF), forced expiratory volume in one second (FEV1), and exhaled nitric oxide (NO). We assessed heart rate variability (HRV) by obtaining 24-hour ambulatory electrocardiograms. RESULTS: The total blood leukocytes and neutrophils increased after the work shift, whereas IL-1β and E-selectin decreased significantly. There were no statistically significant changes in exhaled NO, FEV1, PEF or HRV. CONCLUSION: Occupational exposure to welding fumes and particles caused a slight, acute inflammatory effect estimated based on the increased values of leukocytes and neutrophils in blood and a decrease in the interleukin 1β and E-selectin values, but no changes in the pulmonary function (exhaled NO, FEV1, PEF) or HRV during the working day were observed.
Authors: Huiqi Li; Maria Hedmer; Monica Kåredal; Jonas Björk; Leo Stockfelt; Håkan Tinnerberg; Maria Albin; Karin Broberg Journal: PLoS One Date: 2015-07-06 Impact factor: 3.240
Authors: Mohammad B Hossain; Huiqi Li; Maria Hedmer; Håkan Tinnerberg; Maria Albin; Karin Broberg Journal: Occup Environ Med Date: 2015-09-22 Impact factor: 4.402
Authors: Clarice Alves Bonow; Marta Regina Cezar-Vaz; Lauro Roberto Witt da Silva; Laurelize Pereira Rocha; Claudia Turik Journal: Rev Lat Am Enfermagem Date: 2014 Jan-Feb
Authors: Neserin Ali; Stefan Ljunggren; Helen M Karlsson; Aneta Wierzbicka; Joakim Pagels; Christina Isaxon; Anders Gudmundsson; Jenny Rissler; Jörn Nielsen; Christian H Lindh; Monica Kåredal Journal: Clin Proteomics Date: 2018-05-11 Impact factor: 3.988
Authors: Johanna Samulin Erdem; Yke Jildouw Arnoldussen; Sepideh Tajik; Dag G Ellingsen; Shanbeh Zienolddiny Journal: Toxicol Ind Health Date: 2020-10-07 Impact factor: 2.273