Literature DB >> 23689895

Schmallenberg virus.

K Wernike1, B Hoffmann, M Beer.   

Abstract

In late 2011 a novel virus of the Simbu serogroup, family Bunyaviridae, genus Orthobunyavirus, was discovered at the German-Dutch border and named "Schmallenberg virus" (SBV). Since then, the virus has spread rapidly to other European countries, and the involvement of biting midges has been demonstrated. Affected adult ruminants show none or only mild clinical signs including fever, reduced milk production or diarrhoea. However, in keeping with related viruses, an infection of SBV-naive cows and ewes during a critical period of pregnancy can lead to severe foetal malformations summarized as "arthrogryposis- hydranencephaly syndrome." Diagnostic assays like real-time RT-PCR and antibody ELISA are now available; and substantial knowledge of this virus has been gathered quickly. However, further research and exchange of information are essential.

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Year:  2013        PMID: 23689895     DOI: 10.1159/000312546

Source DB:  PubMed          Journal:  Dev Biol (Basel)        ISSN: 1424-6074


  4 in total

1.  Rapid genome detection of Schmallenberg virus and bovine viral diarrhea virus by use of isothermal amplification methods and high-speed real-time reverse transcriptase PCR.

Authors:  Andrea Aebischer; Kerstin Wernike; Bernd Hoffmann; Martin Beer
Journal:  J Clin Microbiol       Date:  2014-03-19       Impact factor: 5.948

2.  Dynamics of Schmallenberg virus infection within a cattle herd in Germany, 2011.

Authors:  K Wernike; C Silaghi; M Nieder; M Pfeffer; M Beer
Journal:  Epidemiol Infect       Date:  2013-10-16       Impact factor: 4.434

3.  Generation of recombinant Schmallenberg virus nucleocapsid protein in yeast and development of virus-specific monoclonal antibodies.

Authors:  Justas Lazutka; Aurelija Zvirbliene; Indre Dalgediene; Rasa Petraityte-Burneikiene; Aliona Spakova; Vilimas Sereika; Raimundas Lelesius; Kerstin Wernike; Martin Beer; Kestutis Sasnauskas
Journal:  J Immunol Res       Date:  2014-05-29       Impact factor: 4.818

4.  Experimental Infection of Sheep at 45 and 60 Days of Gestation with Schmallenberg Virus Readily Led to Placental Colonization without Causing Congenital Malformations.

Authors:  Ludovic Martinelle; Antoine Poskin; Fabiana Dal Pozzo; Nick De Regge; Brigitte Cay; Claude Saegerman
Journal:  PLoS One       Date:  2015-09-29       Impact factor: 3.240

  4 in total

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