Literature DB >> 23689706

Intraocular penetration of intravenous micafungin in inflamed human eyes.

Kiyofumi Mochizuki1, Akira Sawada, Shinsuke Suemori, Hideaki Kawakami, Yoshiaki Niwa, Yuji Kondo, Kiyofumi Ohkusu, Noriaki Yamada, Shinji Ogura, Takashi Yaguchi, Kazuko Nishimura, Satoshi Kishino.   

Abstract

Eight eyes of 7 patients with fungal disease received intravenous injections of 150 to 300 mg micafungin, and samples of blood, cornea, retina-choroid, aqueous humor, and vitreous humor were collected. The micafungin levels in all collected samples exceeded the MICs; however, the levels in the vitreous and aqueous humors were lower. Our findings suggest that intravenous micafungin should be given in combination with intravitreal antifungal agents after vitrectomy in severe cases of intraocular fungal diseases.

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Year:  2013        PMID： 23689706      PMCID： PMC3719741          DOI： 10.1128/AAC.02300-12

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  16 in total

1.  Intraocular penetration of micafungin in patient with Candida albicans endophthalmitis.

Authors:  Kiyofumi Mochizuki; Shinsuke Suemori; Kazunari Udo; Shinya Komori; Kiyofumi Ohkusu; Noriaki Yamada; Shinji Ogura
Journal:  J Ocul Pharmacol Ther       Date:  2011-07-13       Impact factor: 2.671

2.  Bacillus cereus-induced permeability of the blood-ocular barrier during experimental endophthalmitis.

Authors:  Andrea L Moyer; Raniyah T Ramadan; Billy D Novosad; Roger Astley; Michelle C Callegan
Journal:  Invest Ophthalmol Vis Sci       Date:  2009-03-05       Impact factor: 4.799

3.  Intraocular penetration of voriconazole and caspofungin in a patient with fungal endophthalmitis.

Authors:  Isabel Spriet; Lien Delaere; Katrien Lagrou; Willy E Peetermans; Johan Maertens; Ludo Willems
Journal:  J Antimicrob Chemother       Date:  2009-08-14       Impact factor: 5.790

4.  Detection and identification of fungal pathogens by PCR and by ITS2 and 5.8S ribosomal DNA typing in ocular infections.

Authors:  C Ferrer; F Colom; S Frasés; E Mulet; J L Abad; J L Alió
Journal:  J Clin Microbiol       Date:  2001-08       Impact factor: 5.948

5.  Echinocandin and triazole antifungal susceptibility profiles for Candida spp., Cryptococcus neoformans, and Aspergillus fumigatus: application of new CLSI clinical breakpoints and epidemiologic cutoff values to characterize resistance in the SENTRY Antimicrobial Surveillance Program (2009).

Authors:  Michael A Pfaller; Mariana Castanheira; Shawn A Messer; Gary J Moet; Ronald N Jones
Journal:  Diagn Microbiol Infect Dis       Date:  2011-01       Impact factor: 2.803

6.  Compartmental pharmacokinetics and tissue distribution of the antifungal echinocandin lipopeptide micafungin (FK463) in rabbits.

Authors:  A H Groll; D Mickiene; V Petraitis; R Petraitiene; K H Ibrahim; S C Piscitelli; I Bekersky; T J Walsh
Journal:  Antimicrob Agents Chemother       Date:  2001-12       Impact factor: 5.191

7.  Ocular distribution of intravenously administered micafungin in rabbits.

Authors:  Takashi Suzuki; Toshihiko Uno; Guangming Chen; Yuichi Ohashi
Journal:  J Infect Chemother       Date:  2008-06-24       Impact factor: 2.211

Review 8.  Voriconazole in the treatment of fungal eye infections: a review of current literature.

Authors:  S M Hariprasad; W F Mieler; T K Lin; W E Sponsel; J R Graybill
Journal:  Br J Ophthalmol       Date:  2008-07       Impact factor: 4.638

Review 9.  Clinical aspects of invasive candidiasis: endocarditis and other localized infections.

Authors:  Mario Venditti
Journal:  Drugs       Date:  2009       Impact factor: 9.546

10.  Infectious keratitis caused by Aspergillus tubingensis.

Authors:  László Kredics; János Varga; Sándor Kocsubé; Revathi Rajaraman; Anita Raghavan; Ilona Dóczi; Madhavan Bhaskar; Tibor Mihály Németh; Zsuzsanna Antal; Narendran Venkatapathy; Csaba Vágvölgyi; Robert A Samson; Manoharan Chockaiya; Manikandan Palanisamy
Journal:  Cornea       Date:  2009-09       Impact factor: 2.651
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  18 in total

1.  Efficacy and Pharmacokinetics of Fosmanogepix (APX001) in the Treatment of Candida Endophthalmitis and Hematogenous Meningoencephalitis in Nonneutropenic Rabbits.

Authors:  Ruta Petraitiene; Vidmantas Petraitis; Bo Bo Win Maung; Robert S Mansbach; Michael R Hodges; Malcolm A Finkelman; Karen Joy Shaw; Thomas J Walsh
Journal:  Antimicrob Agents Chemother       Date:  2021-02-17       Impact factor: 5.191

2.  Prevalence of, and risk factors for, hematogenous fungal endophthalmitis in patients with Candida bloodstream infection.

Authors:  Hideaki Kato; Yukihiro Yoshimura; Yoshihiro Suido; Kazuo Ide; Yoshifumi Sugiyama; Kasumi Matsuno; Hideaki Nakajima
Journal:  Infection       Date:  2018-06-29       Impact factor: 3.553

Review 3.  Pharmacokinetics of antifungal drugs: practical implications for optimized treatment of patients.

Authors:  Romuald Bellmann; Piotr Smuszkiewicz
Journal:  Infection       Date:  2017-07-12       Impact factor: 3.553

Review 4.  Bacterial and Fungal Endophthalmitis.

Authors:  Marlene L Durand
Journal:  Clin Microbiol Rev       Date:  2017-07       Impact factor: 26.132

Review 5.  Antimicrobial guide to posterior segment infections.

Authors:  Tapan P Patel; David N Zacks; Vaidehi S Dedania
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2020-11-06       Impact factor: 3.117

Review 6.  Fungal keratitis: Mechanisms of infection and management strategies.

Authors:  Christopher Donovan; Eduardo Arenas; Ramesh S Ayyala; Curtis E Margo; Edgar M Espana
Journal:  Surv Ophthalmol       Date:  2021-08-20       Impact factor: 6.197

Review 7.  Administration and Dosing of Systemic Antifungal Agents in Pediatric Patients.

Authors:  Kevin J Downes; Brian T Fisher; Nicole R Zane
Journal:  Paediatr Drugs       Date:  2020-04       Impact factor: 3.022

8.  Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America.

Authors:  Peter G Pappas; Carol A Kauffman; David R Andes; Cornelius J Clancy; Kieren A Marr; Luis Ostrosky-Zeichner; Annette C Reboli; Mindy G Schuster; Jose A Vazquez; Thomas J Walsh; Theoklis E Zaoutis; Jack D Sobel
Journal:  Clin Infect Dis       Date:  2015-12-16       Impact factor: 9.079

9.  Factors associated with the development of ocular candidiasis and ocular prognosis with echinocandin therapy for candidemia.

Authors:  Daiki Sakai; Wataru Matsumiya; Sentaro Kusuhara; Makoto Nakamura
Journal:  J Ophthalmic Inflamm Infect       Date:  2021-06-14

10.  First case of fungal keratitis caused by Pestalotiopsis clavispora.

Authors:  Yu Monden; Shohaku Yamamoto; Ryoji Yamakawa; Atsuko Sunada; Seishi Asari; Koichi Makimura; Yoshitsugu Inoue
Journal:  Clin Ophthalmol       Date:  2013-11-27
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