Literature DB >> 23689630

Cancer therapeutics: Pulling the plug on BCL-X(L).

Paul S Jeng1, Emily H Cheng.   

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Year:  2013        PMID： 23689630     DOI： 10.1038/nchembio.1256

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


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  10 in total

Review 1.  Targeting the B-cell lymphoma/leukemia 2 family in cancer.

Authors:  Matthew S Davids; Anthony Letai
Journal:  J Clin Oncol       Date:  2012-05-29       Impact factor: 44.544

Review 2.  The BCL-2 protein family: opposing activities that mediate cell death.

Authors:  Richard J Youle; Andreas Strasser
Journal:  Nat Rev Mol Cell Biol       Date:  2008-01       Impact factor: 94.444

3.  Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis.

Authors:  Peter E Czabotar; Dana Westphal; Grant Dewson; Stephen Ma; Colin Hockings; W Douglas Fairlie; Erinna F Lee; Shenggen Yao; Adeline Y Robin; Brian J Smith; David C S Huang; Ruth M Kluck; Jerry M Adams; Peter M Colman
Journal:  Cell       Date:  2013-01-31       Impact factor: 41.582

4.  BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program.

Authors:  Decheng Ren; Ho-Chou Tu; Hyungjin Kim; Gary X Wang; Gregory R Bean; Osamu Takeuchi; John R Jeffers; Gerard P Zambetti; James J-D Hsieh; Emily H-Y Cheng
Journal:  Science       Date:  2010-12-03       Impact factor: 47.728

5.  From mitochondrial biology to magic bullet: navitoclax disarms BCL-2 in chronic lymphocytic leukemia.

Authors:  Loren D Walensky
Journal:  J Clin Oncol       Date:  2011-12-19       Impact factor: 44.544

6.  ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets.

Authors:  Andrew J Souers; Joel D Leverson; Erwin R Boghaert; Scott L Ackler; Nathaniel D Catron; Jun Chen; Brian D Dayton; Hong Ding; Sari H Enschede; Wayne J Fairbrother; David C S Huang; Sarah G Hymowitz; Sha Jin; Seong Lin Khaw; Peter J Kovar; Lloyd T Lam; Jackie Lee; Heather L Maecker; Kennan C Marsh; Kylie D Mason; Michael J Mitten; Paul M Nimmer; Anatol Oleksijew; Chang H Park; Cheol-Min Park; Darren C Phillips; Andrew W Roberts; Deepak Sampath; John F Seymour; Morey L Smith; Gerard M Sullivan; Stephen K Tahir; Chris Tse; Michael D Wendt; Yu Xiao; John C Xue; Haichao Zhang; Rod A Humerickhouse; Saul H Rosenberg; Steven W Elmore
Journal:  Nat Med       Date:  2013-01-06       Impact factor: 53.440

7.  PUMA and BIM are required for oncogene inactivation-induced apoptosis.

Authors:  Gregory R Bean; Yogesh Tengarai Ganesan; Yiyu Dong; Shugaku Takeda; Han Liu; Po M Chan; Yafen Huang; Lewis A Chodosh; Gerard P Zambetti; James J-D Hsieh; Emily H-Y Cheng
Journal:  Sci Signal       Date:  2013-03-26       Impact factor: 8.192

8.  Structure-guided design of a selective BCL-X(L) inhibitor.

Authors:  Guillaume Lessene; Peter E Czabotar; Brad E Sleebs; Kerry Zobel; Kym N Lowes; Jerry M Adams; Jonathan B Baell; Peter M Colman; Kurt Deshayes; Wayne J Fairbrother; John A Flygare; Paul Gibbons; Wilhelmus J A Kersten; Sanji Kulasegaram; Rebecca M Moss; John P Parisot; Brian J Smith; Ian P Street; Hong Yang; David C S Huang; Keith G Watson
Journal:  Nat Chem Biol       Date:  2013-04-21       Impact factor: 15.040

9.  Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.

Authors:  Hyungjin Kim; Ho-Chou Tu; Decheng Ren; Osamu Takeuchi; John R Jeffers; Gerard P Zambetti; James J-D Hsieh; Emily H-Y Cheng
Journal:  Mol Cell       Date:  2009-11-13       Impact factor: 17.970

10.  The landscape of somatic copy-number alteration across human cancers.

Authors:  Rameen Beroukhim; Craig H Mermel; Dale Porter; Guo Wei; Soumya Raychaudhuri; Jerry Donovan; Jordi Barretina; Jesse S Boehm; Jennifer Dobson; Mitsuyoshi Urashima; Kevin T Mc Henry; Reid M Pinchback; Azra H Ligon; Yoon-Jae Cho; Leila Haery; Heidi Greulich; Michael Reich; Wendy Winckler; Michael S Lawrence; Barbara A Weir; Kumiko E Tanaka; Derek Y Chiang; Adam J Bass; Alice Loo; Carter Hoffman; John Prensner; Ted Liefeld; Qing Gao; Derek Yecies; Sabina Signoretti; Elizabeth Maher; Frederic J Kaye; Hidefumi Sasaki; Joel E Tepper; Jonathan A Fletcher; Josep Tabernero; José Baselga; Ming-Sound Tsao; Francesca Demichelis; Mark A Rubin; Pasi A Janne; Mark J Daly; Carmelo Nucera; Ross L Levine; Benjamin L Ebert; Stacey Gabriel; Anil K Rustgi; Cristina R Antonescu; Marc Ladanyi; Anthony Letai; Levi A Garraway; Massimo Loda; David G Beer; Lawrence D True; Aikou Okamoto; Scott L Pomeroy; Samuel Singer; Todd R Golub; Eric S Lander; Gad Getz; William R Sellers; Matthew Meyerson
Journal:  Nature       Date:  2010-02-18       Impact factor: 49.962
  10 in total
  5 in total

1.  Dynamics of the BH3-Only Protein Binding Interface of Bcl-xL.

Authors:  Xiaorong Liu; Alex Beugelsdijk; Jianhan Chen
Journal:  Biophys J       Date:  2015-09-01       Impact factor: 4.033

Review 2.  Direct Activation of Bax Protein for Cancer Therapy.

Authors:  Zhiqing Liu; Ye Ding; Na Ye; Christopher Wild; Haiying Chen; Jia Zhou
Journal:  Med Res Rev       Date:  2015-09-23       Impact factor: 12.944

3.  LOC285629 regulates cell proliferation and motility in colorectal cancer cells.

Authors:  S N Nasir; N Abu; N S Ab Mutalib; M Ishak; I Sagap; L Mazlan; I M Rose; R Jamal
Journal:  Clin Transl Oncol       Date:  2017-11-02       Impact factor: 3.405

Review 4.  Endiandric Acid Derivatives and Other Constituents of Plants from the Genera Beilschmiedia and Endiandra (Lauraceae).

Authors:  Bruno Ndjakou Lenta; Jean Rodolphe Chouna; Pepin Alango Nkeng-Efouet; Norbert Sewald
Journal:  Biomolecules       Date:  2015

5.  Expression of ERCC1, Bcl-2, Lin28a, and Ki-67 as biomarkers of response to first-line platinum-based chemotherapy in patients with high-grade extrapulmonary neuroendocrine carcinomas or small cell lung cancer.

Authors:  Juliana Florinda de M Rêgo; Raphael Salles Scortegagna de Medeiros; Maria Ignez Braghiroli; Breno Galvão; João Evangelista Bezerra Neto; Rodrigo Ramella Munhoz; Juliana Guerra; Suely Nonogaki; Lidia Kimura; Tulio Eduardo Pfiffer; Gilberto de Castro; Paulo Marcelo Hoff; Duilio Rocha Filho; Frederico Perego Costa; Rachel P Riechelmann
Journal:  Ecancermedicalscience       Date:  2017-09-11
  5 in total

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